Browsing by Author "Gee, Elaine Pei-San"

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Biophysical and Molecular Determinants in Cell Tension-Mediated Fibronectin Unfolding that Drive Fibrillogenesis

Gee, Elaine Pei-San (2013-02-20)

Assembly of the extracellular matrix (ECM) protein fibronectin (FN) is a mechanical process that involves cell binding to FN through cell surface integrin receptors and application of tensional forces generated in the ...
Fibronectin Unfolding Revisited: Modeling Cell Traction-Mediated Unfolding of the Tenth Type-III Repeat

Gee, Elaine Pei-San; Ingber, Donald Elliott; Stultz, Collin Melveton (Public Library of Science, 2008)

Fibronectin polymerization is essential for the development and repair of the extracellular matrix. Consequently, deciphering the mechanism of fibronectin fibril formation is of immense interest. Fibronectin fibrillogenesis ...