Browsing by Author "Allen, Paul"

Now showing items 1-4 of 4

    • Blood-Based Biomarkers of Aggressive Prostate Cancer 

      Liong, Men Long; Lim, Chun Ren; Yang, Hengxuan; Chao, Samuel; Bong, Chin Wei; Leong, Wing Seng; Das, Prashanta Kumar; Loh, Chit Sin; Lau, Ban Eng; Yu, Choon Geok; Ooi, Edie Jian Jiek; Nam, Robert K.; Allen, Paul Denney; Steele, Graeme S.; Wassmann, Karl; Richie, Jerome Paul; Liew, Choong Chin (Public Library of Science, 2012)
      Purpose: Prostate cancer is a bimodal disease with aggressive and indolent forms. Current prostate-specific-antigen testing and digital rectal examination screening provide ambiguous results leading to both under-and ...

    • Measurement of RyR Permeability Reveals a Role of Calsequestrin in Termination of SR \(Ca^{2+}\) Release in Skeletal Muscle 

      Sztretye, Monika; Yi, Jianxun; Figueroa, Lourdes; Zhou, Jingsong; Royer, Leandro; Allen, Paul Denney; Brum, Gustavo; Ríos, Eduardo (The Rockefeller University Press, 2011)
      The mechanisms that terminate \(Ca^{2+}\) release from the sarcoplasmic reticulum are not fully understood. D4cpv-Casq1 (Sztretye et al. 2011. J. Gen. Physiol. doi:10.1085/jgp.201010591) was used in mouse skeletal muscle ...

    • Nifedipine Treatment Reduces Resting Calcium Concentration, Oxidative and Apoptotic Gene Expression, and Improves Muscle Function in Dystrophic mdx Mice 

      Altamirano, Francisco; Valladares, Denisse; Henríquez-Olguín, Carlos; Casas, Mariana; López, Jose R.; Allen, Paul D.; Jaimovich, Enrique (Public Library of Science, 2013)
      Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of ...

    • Whole Body Periodic Acceleration Is an Effective Therapy to Ameliorate Muscular Dystrophy in mdx Mice 

      Altamirano, Francisco; Perez, Claudio F.; Liu, Min; Widrick, Jeffrey; Barton, Elisabeth R.; Allen, Paul D.; Adams, Jose A.; Lopez, Jose R. (Public Library of Science, 2014)
      Duchenne muscular dystrophy (DMD) is a genetic disorder caused by the absence of dystrophin in both skeletal and cardiac muscles. This leads to severe muscle degeneration, and dilated cardiomyopathy that produces patient ...