Browsing by Author "Calarco, John A"
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Heritable genome editing in C. elegans via a CRISPR-Cas9 system
Friedland, Ari E.; Tzur, Yonatan B.; Esvelt, Kevin M.; Colaiácovo, Monica P.; Church, George M.; Calarco, John A. (2013)CRISPR-Cas systems have been used with single-guide RNAs for accurate gene disruption and conversion in multiple biological systems. Here we report the use of the endonuclease Cas9 to target genomic sequences in the C. ...