Browsing by Author "Liang, Xiaoliang"

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Fatty Acid Binding Protein 4 Deficiency Protects against Oxygen-Induced Retinopathy in Mice

Saint-Geniez, Magali; Ghelfi, Elisa; Liang, Xiaoliang; Yu, Chenwei; Spencer, Carrie; Abend, Stephanie; Hotamisligil, Gokhan; Cataltepe, Sule (Public Library of Science, 2014)

Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide due to increasing survival rates of premature infants. Initial suppression, followed by increased production of the retinal vascular ...
Flotillin-2 Modulates Fas Signaling Mediated Apoptosis after Hyperoxia in Lung Epithelial Cells

Wei, Shuquan; Moon, Hyung-Geun; Zheng, Yijie; Liang, Xiaoliang; An, Chang Hyeok; Jin, Yang (Public Library of Science, 2013)

Lipid rafts are subdomains of the cell membrane with distinct protein composition and high concentrations of cholesterol and glycosphingolipids. Raft proteins are thought to mediate diverse cellular processes including ...
P62 Sequestosome 1/Light Chain 3b Complex Confers Cytoprotection on Lung Epithelial Cells After Hyperoxia

Liang, Xiaoliang; Fung, James; Tanaka, Akihiko; Choi, Augustine; Jin, Yang; Wei, Shu-Quan; Lee, Seon-Jin; Zhang, Meng (American Thoracic Society, 2013)

Lung epithelial cell death is a prominent feature of hyperoxic lung injury, and has been considered a very important underlying mechanism of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Here we ...