Browsing by Author "Sharp, Phillip A."

Now showing items 1-2 of 2

    • A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells 

      Zheng, Grace X. Y.; Medeiros, Lea A.; Kirak, Oktay; Dennis, Lucas M.; Jaenisch, Rudolf; Burge, Christopher B.; Ravi, Arvind; Calabrese, Joseph Michael; McManus, Michael Louis; Sharp, Phillip A. (Public Library of Science, 2011)
      MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal cellular functions, others are likely relevant in more specific ...

    • miRNA Profiling of Naïve, Effector and Memory CD8 T Cells 

      Wu, Haoquan; Neilson, Joel R.; Kumar, Priti; Manocha, Monika; Shankar, Premlata; Sharp, Phillip A.; Manjunath, N. (Public Library of Science, 2007)
      microRNAs have recently emerged as master regulators of gene expression during development and cell differentiation. Although profound changes in gene expression also occur during antigen-induced T cell differentiation, ...