Now showing items 1-20 of 50

    • A 3D interactive multi-object segmentation tool using local robust statistics driven active contours 

      Gao, Yi; Kikinis, Ron; Bouix, Sylvain; Shenton, Martha Elizabeth; Tannenbaum, Allen (Elsevier BV, 2012)
      Extracting anatomical and functional significant structures renders one of the important tasks for both the theoretical study of the medical image analysis, and the clinical and practical community. In the past, much work ...
    • Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography study 

      Rosenberger, Gudrun; Nestor, Paul Gerard; Oh, Jungsu S.; Levitt, James Jonathan; Kindleman, Gordon; Bouix, Sylvain; Fitzsimmons, Jennifer J; Niznikiewicz, Margaret A.; Westin, Carl-Fredrik; Kikinis, Ron; McCarley, Robert William; Shenton, Martha Elizabeth; Kubicki, Marek R. (Springer Science + Business Media, 2012)
      Thalamo-cortical feedback loops play a key role in the processing and coordination of processing and integration of perceptual inputs and outputs, and disruption in this connection has long been hypothesized to contribute ...
    • Atlas-Guided Segmentation of Vervet Monkey Brain MRI 

      Fedorov, Andriy; Li, Xiaoxing; Pohl, Kilian M; Bouix, Sylvain; Styner, Martin; Addicott, Merideth; Wyatt, Chris; Daunais, James B; Wells, William Mercer; Kikinis, Ron (Bentham Science, 2011)
      The vervet monkey is an important nonhuman primate model that allows the study of isolated environmental factors in a controlled environment. Analysis of monkey MRI often suffers from lower quality images compared with ...
    • Auditory verbal hallucinations and the interhemispheric auditory pathway in chronic schizophrenia 

      Wigand, Marlene; Kubicki, Marek R.; Clemm von Hohenberg, Christian; Leicht, Gregor; Karch, Susanne; Eckbo, Ryan; Pelavin, Paula E.; Hawley, Kathryn; Rujescu, Dan; Bouix, Sylvain; Shenton, Martha Elizabeth; Mulert, Christoph (Informa UK Limited, 2014)
      Objectives—The interhemispheric auditory pathway has been shown to play a crucial role in the processing of acoustic stimuli, and alterations of structural and functional connectivity between bilateral auditory areas are ...
    • Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia 

      Asami, Takeshi; Hyuk Lee, Sang; Bouix, Sylvain; Rathi, Yogesh; Whitford, Thomas; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; McCarley, Robert William; Shenton, Martha Elizabeth; Kubicki, Marek R. (Elsevier BV, 2014)
      Although diffusion tensor imaging (DTI) studies have reported fractional anisotropy (FA) abnormalities in multiple white matter (WM) regions in schizophrenia, relationship between abnormal FA and negative symptoms has not ...
    • CNTNAP2 polymorphisms and structural brain connectivity: A diffusion-tensor imaging study 

      Clemm von Hohenberg, Christian; Wigand, Marlene C.; Kubicki, Marek R.; Leicht, Gregor; Giegling, Ina; Karch, Susanne; Hartmann, Annette M.; Konte, Bettina; Friedl, Marion; Ballinger, Thomas; Eckbo, Ryan; Bouix, Sylvain; Jäger, Lorenz; Shenton, Martha Elizabeth; Rujescu, Dan; Mulert, Christoph (Elsevier BV, 2013)
      CNTNAP2 is a gene on chromosome 7 that has shown associations with autism andschizophrenia, and there is evidence that it plays an important role for neuronal synchronization and brain connectivity. In this study, we ...
    • Directional functions for orientation distribution estimation 

      Rathi, Yogesh; Michailovich, Oleg; Shenton, Martha Elizabeth; Bouix, Sylvain (Elsevier BV, 2009)
      Computing the Orientation Distribution Function (ODF) from High Angular Resolution Diffusion Imaging (HARDI) signals makes it possible to determine the orientation of fiber bundles of the brain. The HARDI signals are samples ...
    • Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia 

      Whitford, T; Mathalon, D. H.; Shenton, Martha Elizabeth; Roach, B. J.; Bammer, R.; Adcock, R. A.; Bouix, Sylvain; Kubicki, Marek R.; De Siebenthal, J.; Rausch, A. C.; Schneiderman, J. S.; Ford, J. M. (Cambridge University Press (CUP), 2010)
      Patients with schizophrenia (SZ) characteristically exhibit supranormal levels of cortical activity to self-induced sensory stimuli, ostensibly because of abnormalities in the neural signals (corollary discharges, CDs) ...
    • An elliptic PDE approach for shape characterization 

      Haidar, H.; Bouix, Sylvain; Levitt, James Jonathan; McCarley, Robert William; Shenton, Martha Elizabeth; Soul, Janet (IEEE, 2004)
      This paper presents a novel approach to analyze the shape of anatomical structures. Our methodology is rooted in classical physics and in particular Poisson's equation, a fundamental partial differential equation [1]. The ...
    • Excessive Extracellular Volume Reveals a Neurodegenerative Pattern in Schizophrenia Onset 

      Pasternak, Ofer; Westin, Carl-Fredrik; Bouix, Sylvain; Seidman, Larry Joel; Goldstein, Jill M.; Woo, Tsung-Ung Wilson; Petryshen, Tracey Lynn; Mesholam-Gately, Raquelle; McCarley, Robert William; Kikinis, Ron; Shenton, Martha Elizabeth; Kubicki, Marek R. (Society for Neuroscience, 2012)
      Diffusion MRI has been successful in identifying the existence of white matter abnormalities in schizophrenia in vivo. However, the role of these abnormalities in the etiology of schizophrenia is not well understood. ...
    • Fiber Bundle Estimation and Parameterization 

      Niethammer, Marc; Bouix, Sylvain; Westin, Carl-Fredrik; Shenton, Martha Elizabeth (Springer Science + Business Media, 2006)
      Individual white matter fibers cannot be resolved by current magnetic resonance (MR) technology. Many fibers of a fiber bundle will pass through an individual volume element (voxel). Individual visualized fiber tracts are ...
    • Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection 

      Whitford, Thomas; Savadjiev, Peter; Kubicki, Marek R.; O, Lauren J.; Terry, Douglas P.; Bouix, Sylvain; Westin, Carl-Fredrik; Schneiderman, Jason S.; Bobrow, Laurel; Rausch, Andrew C.; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; Pantelis, Christos; Wood, Stephen J.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2011)
      Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
    • A filtered approach to neural tractography using the Watson directional function 

      Malcolm, James G.; Michailovich, Oleg; Bouix, Sylvain; Westin, Carl-Fredrik; Shenton, Martha Elizabeth; Rathi, Yogesh (Elsevier BV, 2010)
      We propose a technique to simultaneously estimate the local fiber orientations and perform multifiber tractography. Existing techniques estimate the local fiber orientation at each voxel independently so there is no running ...
    • Genetic contributions to changes of fiber tracts of ventral visual stream in 22q11.2 deletion syndrome 

      Kikinis, Zora; Makris, Nikos; Finn, Christine; Bouix, Sylvain; Lucia, Diandra; Coleman, Michael James; Tworog-Dube, Erica; Kikinis, Ron; Kucherlapati, Raju; Shenton, Martha Elizabeth; Kubicki, Marek R. (Springer Science + Business Media, 2013)
      Patients with 22q11.2 deletion syndrome (22q11.2DS) represent a population at high risk for developing schizophrenia, as well as learning disabilities. Deficits in visuo-spatial memory are thought to underlie some of the ...
    • Global Medical Shape Analysis Using the Laplace-Beltrami Spectrum 

      Niethammer, Marc; Reuter, Martin; Wolter, Franz-Erich; Bouix, Sylvain; Peinecke, Niklas; Koo, Min-Seong; Shenton, Martha Elizabeth (Springer, 2007)
      This paper proposes to use the Laplace-Beltrami spectrum (LBS) as a global shape descriptor for medical shape analysis, allowing for shape comparisons using minimal shape preprocessing: no registration, mapping, or remeshing ...
    • Gray matter alterations in early aging: A diffusion magnetic resonance imaging study 

      Rathi, Yogesh; Pasternak, Ofer; Savadjiev, Peter; Michailovich, O.; Bouix, Sylvain; Kubicki, Marek R.; Westin, Carl-Fredrik; Makris, Nikolaos; Shenton, Martha Elizabeth (Wiley-Blackwell, 2013)
      Many studies have observed altered neurofunctional and structural organization in the aging brain. These observations from functional neuroimaging studies show a shift in brain activity from the posterior to the anterior ...
    • A Hierarchical Algorithm for MR Brain Image Parcellation 

      Pohl, Kilian M.; Bouix, Sylvain; Nakamura, Motoaki; Rohlfing, Torsten; McCarley, Robert William; Kikinis, Ron; Grimson, W. Eric L.; Shenton, Martha Elizabeth; Wells, William Mercer (Institute of Electrical and Electronics Engineers (IEEE), 2007)
      We introduce an algorithm for segmenting brain magnetic resonance (MR) images into anatomical compartments such as the major tissue classes and neuro-anatomical structures of the gray matter. The algorithm is guided by ...
    • Hockey Concussion Education Project, Part 2. Microstructural white matter alterations in acutely concussed ice hockey players: a longitudinal free-water MRI study 

      Pasternak, Ofer; Koerte, Inga Katharina; Bouix, Sylvain; Fredman, Eli; Sasaki, Takeshi; Mayinger, Michael; Helmer, Karl G.; Johnson, Andrew M.; Holmes, Jeffrey D.; Forwell, Lorie A.; Skopelja, Elaine N.; Shenton, Martha Elizabeth; Echlin, Paul S. (Journal of Neurosurgery Publishing Group (JNSPG), 2014)
      Object—Concussion is a common injury in ice hockey and a health problem for the general population. Traumatic axonal injury has been associated with concussions (also referred to as mild traumatic brain injuries), yet the ...
    • Hockey Concussion Education Project, Part 3. White matter microstructure in ice hockey players with a history of concussion: a diffusion tensor imaging study 

      Sasaki, Takeshi; Pasternak, Ofer; Mayinger, Michael; Muehlmann, Marc; Savadjiev, Peter; Bouix, Sylvain; Kubicki, Marek R.; Fredman, Eli; Dahlben, Brian; Helmer, Karl G.; Johnson, Andrew M.; Holmes, Jeffrey D.; Forwell, Lorie A.; Skopelja, Elaine N.; Shenton, Martha Elizabeth; Echlin, Paul S.; Koerte, Inga Katharina (Journal of Neurosurgery Publishing Group (JNSPG), 2014)
      Object—The aim of this study was to examine the brain’s white matter microstructure using magnetic resonance diffusion tensor imaging (DTI) in ice hockey players with a history of clinically symptomatic concussion compared ...
    • An In Vivo MRI Study of Prefrontal Cortical Complexity in First-Episode Psychosis 

      Wiegand, Laura C.; Warfield, Simon Keith; Levitt, James Jonathan; Hirayasu, Yoshio; Salisbury, Dean F.; Heckers, Stephan; Bouix, Sylvain; Schwartz, Daniel; Spencer, Magdalena; Dickey, Chandlee C.; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (American Psychiatric Publishing, 2005)
      Objective: The purpose of this study was to investigate abnormalities in the surface complexity of the prefrontal cortex and in the hemispheric asymmetry of cortical complexity in first-episode patients with schizophrenia. ...