Now showing items 1-5 of 5

    • Cathepsin S Signals via PAR2 and Generates a Novel Tethered Ligand Receptor Agonist 

      Elmariah, Sarina B.; Reddy, Vemuri B.; Lerner, Ethan A. (Public Library of Science, 2014)
      Protease-activated receptor-2 is widely expressed in mammalian epithelial, immune and neural tissues. Cleavage of PAR2 by serine proteases leads to self-activation of the receptor by the tethered ligand SLIGRL. The ...
    • Evoked itch perception is associated with changes in functional brain connectivity 

      Desbordes, Gaëlle; Li, Ang; Loggia, Marco L.; Kim, Jieun; Schalock, Peter C.; Lerner, Ethan; Tran, Thanh N.; Ring, Johannes; Rosen, Bruce R.; Kaptchuk, Ted J.; Pfab, Florian; Napadow, Vitaly (Elsevier, 2014)
      Chronic itch, a highly debilitating condition, has received relatively little attention in the neuroimaging literature. Recent studies suggest that brain regions supporting itch in chronic itch patients encompass sensorimotor ...
    • The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients 

      Napadow, Vitaly J.; Li, Ang; Loggia, Marco Luciano; Kim, Jieun; Mawla, Ishtiaq; Desbordes, Gaelle; Schalock, P. C.; Lerner, Ethan Arthur; Tran, Thanh-Nga Trinh; Ring, Johannes; Rosen, Bruce; Kaptchuk, Ted Jack; Pfab, Florian (Wiley-Blackwell, 2015)
      Background Psychological factors are known to significantly modulate itch in patients suffering from chronic itch. Itch is also highly susceptible to both placebo and nocebo (negative placebo) effects. Brain activity ...
    • OA08.04. Brain circuitry subserving acupuncture relief of itch in atopic dermatitis: an fMRI study 

      Napadow, Vitaly J.; Li, A.; Loggia, Marco Luciano; Kim, J.; Schalock, Peter C.; Lerner, Ethan Arthur; Rosen, Bruce; Kaptchuk, Ted Jack; Pfab, F (BioMed Central, 2012)
    • Transient alterations of cutaneous sensory nerve function by non-invasive cryolipolysis 

      Garibyan, Lilit; Cornelissen, Laura; Sipprell, William; Pruessner, Joachim; Elmariah, Sarina; Luo, Tuan; Lerner, Ethan A.; Jung, Yookyung; Evans, Conor; Zurakowski, David; Berde, Charles B.; Rox Anderson, R. (2015)
      Cryolipolysis is a non-invasive, skin cooling treatment for local fat reduction that causes prolonged hypoesthesia over the treated area. We tested the hypothesis that cryolipolysis can attenuate nociception of a range of ...