Now showing items 1-2 of 2

    • T cell–derived inducible nitric oxide synthase switches off TH17 cell differentiation 

      Yang, Jianjun; Zhang, Ruihua; Lu, Geming; Shen, Yu; Peng, Liang; Zhu, Chen; Cui, Miao; Wang, Weidong; Arnaboldi, Paul; Tang, Meng; Gupta, Monica; Qi, Chen-Feng; Jayaraman, Padmini; Zhu, Hongfa; Jiang, Bo; Chen, Shu-hsia; He, John Cijiang; Ting, Adrian T.; Zhou, Ming-Ming; Kuchroo, Vijay K.; Morse, Herbert C.; Ozato, Keiko; Sikora, Andrew G.; Xiong, Huabao (The Rockefeller University Press, 2013)
      RORγt is necessary for the generation of TH17 cells but the molecular mechanisms for the regulation of TH17 cells are still not fully understood. We show that activation of CD4+ T cells results in the expression of inducible ...
    • Transcription Factor IRF8 Directs a Silencing Programme for TH17 Cell Differentiation 

      Ouyang, Xinshou; Zhang, Ruihua; Yang, Jianjun; Li, Qingshan; Qin, Lihui; Liu, Jianguo; Ning, Huan; Shin, Min Sun; Gupta, Monica; Qi, Chen-Feng; Lira, Sergio A.; Morse, Herbert C.; Ozato, Keiko; Mayer, Lloyd; Xiong, Huabao; Zhu, Cheng; He, John Cijiang (Nature Publishing Group, 2011)
      T\(_H\)17 cells are recognized as a unique subset of T helper cells that have critical roles in the pathogenesis of autoimmunity and tissue inflammation. Although RORγt is necessary for the generation of T\(_H\)17 cells, ...