Browsing by Author "Zheng, Hui"

Now showing items 1-14 of 14

    • The Absence of Obstructive Sleep Apnea May Protect against Non-Alcoholic Fatty Liver in Patients Undergoing Bariatric Surgery 

      Corey, Kathleen Elizabeth; Misdraji, Joseph; Zheng, Zheng; Malecki, Kyle M.; Kneeman, Jacob; Gelrud, Louis; Chung, Raymond Taeyong (Public Library of Science, 2013)
      Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide and its progressive form, steatohepatitis, will be the leading indication for liver transplant by 2020. While risk ...

    • Battery of behavioral tests in mice to study postoperative delirium 

      Peng, Mian; Zhang, Ce; Dong, Yuanlin; Zhang, Yiying; Nakazawa, Harumasa; Kaneki, Masao; Zheng, Hui; Shen, Yuan; Marcantonio, Edward R.; Xie, Zhongcong (Nature Publishing Group, 2016)
      Postoperative delirium is associated with increased morbidity, mortality and cost. However, its neuropathogenesis remains largely unknown, partially owing to lack of animal model(s). We therefore set out to employ a battery ...

    • Circulating Soluble CD163 is Associated with Steatohepatitis and Advanced Fibrosis in Nonalcoholic Fatty Liver Disease 

      Mueller, Jessica L; Feeney, Eoin R; Zheng, Hui; Misdraji, Joseph; Kruger, Annie J; Alatrakchi, Nadia; King, Lindsay Y; Gelrud, Louis; Corey, Kathleen E; Chung, Raymond T (Nature Publishing Group, 2015)
      OBJECTIVES: Soluble CD163 (sCD163), a marker of Kupffer cell activation detectable in serum, correlates with inflammation and fibrosis in chronic viral hepatitis, but its role in nonalcoholic fatty liver disease is unknown. ...

    • A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors 

      Damiano, Edward R.; El-Khatib, Firas H.; Zheng, Hui; Nathan, David M.; Russell, Steven J. (American Diabetes Association, 2013)
      OBJECTIVE To compare three continuous glucose monitoring (CGM) devices in subjects with type 1 diabetes under closed-loop blood glucose (BG) control. RESEARCH DESIGN AND METHODS Six subjects with type 1 diabetes (age 52 ± ...

    • Does Glucose Variability Influence the Relationship Between Mean Plasma Glucose and \(HbA_{1c}\) Levels in Type 1 and Type 2 Diabetic Patients? 

      Kuenen, Judith C.; Borg, Rikke; Kuik, Dirk J.; Zheng, Zheng; Schoenfeld, David Alan; Diamant, Michaela; Nathan, David Matthew; Heine, Robert J. (American Diabetes Association, 2011)
      Objective: The A1C-Derived Average Glucose (ADAG) study demonstrated a linear relationship between \(HbA_{1c}\) and mean plasma glucose (MPG). As glucose variability (GV) may contribute to glycation, we examined the ...

    • Does the Mechanism of Lymph Node Invasion Affect Survival in Patients with Pancreatic Ductal Adenocarcinoma? 

      Konstantinidis, Ioannis T; Deshpande, Vikram; Hui, Hui; Wargo, Jennifer Ann; Fernandez-Del Castillo, Carlos F.; Thayer, Sarah P.; Androutsopoulos, Vasiliki; Lauwers, Gregory Y.; Warshaw, Andrew Louis; Ferrone, Cristina Rosa (Springer Science + Business Media, 2010)
      Background: Lymph node metastases are prognostically significant in pancreatic ductal adenocarcinoma. Little is known about the significance of direct lymph node invasion. Aim: The aim of this study is to find out whether ...

    • Gallbladder Lesions Identified on Ultrasound. Lessons from the Last 10 Years 

      Konstantinidis, Ioannis T; Bajpai, Surabhi; Kambadakone, Avinash R.; Tanabe, Kenneth Kenji; Berger, David Lawrence; Hui, Hui; Sahani, Dushyant V.; Lauwers, Gregory Y.; Fernandez-Del Castillo, Carlos F.; Warshaw, Andrew Louis; Ferrone, Cristina Rosa (Springer Nature, 2011)
      Background: Possible mass lesions identified on ultrasound (US) of the gallbladder may prompt an aggressive surgical intervention due to the possibility of a malignant neoplasm. Aim: This study aims to utilize a large ...

    • Gastric Cancer in Individuals with Li-Fraumeni Syndrome 

      Masciari, Serena; Dewanwala, Akriti; Stoffel, Elena M.; Lauwers, Gregory Y.; Hui, Hui; Achatz, Maria Isabel; Riegert-Johnson, Douglas; Foretova, Lenka; Silva, Edaise M.; Digianni, Lisa; Verselis, Sigitas J.; Schneider, Katherine; Li, Frederick Pei; Fraumeni, Joseph; Garber, Judy Ellen; Syngal, Sapna (Nature Publishing Group, 2011)
      PURPOSE: Li-Fraumeni syndrome is a rare hereditary cancer syndrome associated with germline mutations in the TP53 gene. Although sarcomas, brain tumors, leukemias, breast and adrenal cortical carcinomas are typically ...

    • Pancreatic Ductal Adenocarcinoma: Long-Term Survival Does Not Equal Cure 

      Ferrone, Cristina Rosa; Pieretti-Vanmarcke, Rafael; Bloom, Jordan P; Hui, Hui; Szymonifka, Jackye; Wargo, Jennifer Ann; Thayer, Sarah P.; Lauwers, Gregory Y.; Deshpande, Vikram; Mino-Kenudson, Mari; Fernandez-Del Castillo, Carlos F.; Lillemoe, Keith Douglas; Warshaw, Andrew Louis (Elsevier BV, 2012)
      Background: Pancreatic ductal adenocarcinoma represents 90% of pancreatic cancers and is an important cause of cancer death in the United States. Operative resection remains as the only treatment providing prolonged survival, ...

    • Perioperative and long-term outcomes of liver resection for hepatitis B virus-related hepatocellular carcinoma without versus with hepatic inflow occlusion: study protocol for a prospective randomized controlled trial 

      Xu, Yinzhe; Chen, Jiye; Wang, Hongguang; Zheng, Hui; Feng, Dan; Zhang, Aiqun; Leng, Jianjun; Duan, Weidong; Yang, Zhanyu; Chen, Mingyi; Shi, Xianjie; Cai, Shouwang; Ji, Wenbin; Jiang, Kai; Zhang, Wenzhi; Chen, Yongliang; Gu, Wanqing; Dong, Jiahong; Lu, Shichun (BioMed Central, 2016)
      Background: The high prevalence of hepatitis B virus (HBV) imposes a huge burden of hepatocellular carcinoma (HCC) in Asia. Surgical resection remains an important therapeutic strategy for HCC. Hepatic inflow occlusion, ...

    • Proof-of-Concept, Randomized, Controlled Clinical Trial of Bacillus-Calmette-Guerin for Treatment of Long-Term Type 1 Diabetes 

      Faustman, Denise Louise; Wang, Limei; Okubo, Yoshiaki; Burger, Douglas E.; Ban, Liqin; Man, Guotong; Zheng, Hui; Schoenfeld, David Alan; Pompei, Richard; Avruch, Joseph; Nathan, David Matthew (Public Library of Science, 2012)
      Background: No targeted immunotherapies reverse type 1 diabetes in humans. However, in a rodent model of type 1 diabetes, Bacillus Calmette-Guerin (BCG) reverses disease by restoring insulin secretion. Specifically, it ...

    • Serum Vitamin D Levels are not Predictive of the Progression of Chronic Liver Disease in Hepatitis C Patients with Advanced Fibrosis 

      Corey, Kathleen Elizabeth; Zheng, Zheng; Mendez-Navarro, Jorge; Delgado-Borrego, Aymin; Dienstag, Jules Leonard; Chung, Raymond Taeyong (Public Library of Science, 2012)
      In animal models and human cross-sectional studies, vitamin D deficiency has been associated with liver disease progression. Vitamin D supplementation has been suggested as a treatment to prevent disease progression. We ...

    • Treg activation defect in type 1 diabetes: correction with TNFR2 agonism 

      Okubo, Yoshiaki; Torrey, Heather; Butterworth, John; Zheng, Hui; Faustman, Denise L (Nature Publishing Group, 2016)
      Activated T-regulatory cells (aTregs) prevent or halt various forms of autoimmunity. We show that type 1 diabetics (T1D) have a Treg activation defect through an increase in resting Tregs (rTregs, CD4+CD25+Foxp3+CD45RA) ...

    • Trends in Presentation and Survival for Gallbladder Cancer During a Period of More Than 4 Decades 

      Konstantinidis, Ioannis T; Deshpande, Vikram; Genevay, Muriel; Berger, David Lawrence; Fernandez-Del Castillo, Carlos F.; Tanabe, Kenneth Kenji; Hui, Hui; Lauwers, Gregory Y.; Ferrone, Cristina Rosa (American Medical Association (AMA), 2009)
      Objectives: To determine the prevalence of incidentally found cases of gallbladder cancer, the incidence of residual disease at reexploration, and the changes in the mode of presentation, treatment, and survival of patients ...