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    • Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning 

      Saez, Borja; Ferraro, F.; Yusuf, Rushdia Zareen; Cook, Colleen M.; Yu, Vionnie Wing Chi; Pardo-Saganta, A.; Sykes, Stephen M.; Palchaudhuri, Rahul; Schajnovitz, Amir; Lotinun, S; Lymperi, Stefania; Mendez-Ferrer, Simon; del Toro, Raquel; Day, Robyn Rouviere; Vasic, Radovan; Acharya, Sanket Shyamkant; Baron, Roland; Lin, Charles P.; Yamaguchi, Yu; Wagers, Amy Jo; Scadden, David Thomas (American Society of Hematology, 2014)
      The glycosyltransferase gene, Ext1, is essential for heparan sulfate production. Induced deletion of Ext1 selectively in Mx1-expressing bone marrow (BM) stromal cells, a known population of skeletal stem/progenitor cells, ...