Now showing items 1-3 of 3

    • A branched chain amino acid metabolite drives vascular transport of fat and causes insulin resistance 

      Jang, Cholsoon; Oh, Sungwhan F; Wada, Shogo; Rowe, Glenn C; Liu, Laura; Chan, Mun Chun; Rhee, James; Hoshino, Atsushi; Kim, Boa; Ibrahim, Ayon; Baca, Luisa G; Kim, Esl; Ghosh, Chandra C; Parikh, Samir M; Jiang, Aihua; Chu, Qingwei; Forman, Daniel E.; Lecker, Stewart H.; Krishnaiah, Saikumari; Rabinowitz, Joshua D; Weljie, Aalim M; Baur, Joseph A; Kasper, Dennis L; Arany, Zoltan (2016)
      Epidemiological and experimental data implicate branched chain amino acids (BCAAs) in the development of insulin resistance, but the mechanisms underlying this link remain unclear.1–3 Insulin resistance in skeletal muscle ...
    • Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness 

      Akeju, Oluwaseun; Loggia, Marco L; Catana, Ciprian; Pavone, Kara J; Vazquez, Rafael; Rhee, James; Contreras Ramirez, Violeta; Chonde, Daniel B; Izquierdo-Garcia, David; Arabasz, Grae; Hsu, Shirley; Habeeb, Kathleen; Hooker, Jacob M; Napadow, Vitaly; Brown, Emery N; Purdon, Patrick L (eLife Sciences Publications, Ltd, 2014)
      Understanding the neural basis of consciousness is fundamental to neuroscience research. Disruptions in cortico-cortical connectivity have been suggested as a primary mechanism of unconsciousness. By using a novel combination ...
    • Spatiotemporal Dynamics of Dexmedetomidine-Induced Electroencephalogram Oscillations 

      Akeju, Oluwaseun; Kim, Seong-Eun; Vazquez, Rafael; Rhee, James; Pavone, Kara J.; Hobbs, Lauren E.; Purdon, Patrick L.; Brown, Emery N. (Public Library of Science, 2016)
      An improved understanding of the neural correlates of altered arousal states is fundamental for precise brain state targeting in clinical settings. More specifically, electroencephalogram recordings are now increasingly ...