Now showing items 1-2 of 2

    • RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance 

      Xiao, Yanping; Yu, Sanhong; Zhu, Baogong; Bedoret, Denis; Bu, Xia; Francisco, Loise M.; Hua, Ping; Duke-Cohan, Jonathan S.; Umetsu, Dale T.; Sharpe, Arlene H.; DeKruyff, Rosemarie H.; Freeman, Gordon J. (The Rockefeller University Press, 2014)
      We report that programmed death ligand 2 (PD-L2), a known ligand of PD-1, also binds to repulsive guidance molecule b (RGMb), which was originally identified in the nervous system as a co-receptor for bone morphogenetic ...
    • TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine 

      Jemielity, Stephanie; Wang, Jinyize J.; Chan, Ying Kai; Ahmed, Asim Aminsharif; Li, Wenhui; Monahan, Sheena; Bu, Xia; Farzan, Michael; Freeman, Gordon James; Umetsu, Dale T.; DeKruyff, Rosemarie H.; Choe, Hyeryun (Public Library of Science, 2013)
      Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and ...