Now showing items 1-9 of 9

    • Adequate Relief in a Treatment Trial With IBS Patients: A Prospective Assessment 

      Passos, Maria C F; Lembo, Anthony J.; Conboy, Lisa Ann; Kaptchuk, Ted Jack; Kelly, John M; Quilty, Mary T; Kerr, Catherine; Jacobson, Eric Emil; Hu, Rong; Friedlander, Elizabeth; Drossman, Douglas A (Nature Publishing Group, 2009)
      Background: Adequate relief of IBS symptoms (IBS-AR) has been used as a primary endpoint in many randomized controlled trials of IBS and is considered by the Rome III Committee to be an acceptable primary endpoint. However, ...
    • Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome 

      Kaptchuk, Ted Jack; Kelley, John; Conboy, Lisa Ann; Kerr, Catherine; Davis, Roger B.; Jacobson, Eric Emil; Kirsch, Irving; Schyner, R. N; Nam, B. H.; Nguyen, L. T; Park, Min Hi; Rivers, A. L; McManus, C.; Kokkotou, Efi G.; Drossman, D. A; Goldman, Peter; Lembo, Anthony J. (BMJ, 2008)
      Objective To investigate whether placebo effects can experimentally be separated into the response to three components—assessment and observation, a therapeutic ritual (placebo treatment), and a supportive patient-practitioner ...
    • “Maybe I Made Up the Whole Thing”: Placebos and Patients’ Experiences in a Randomized Controlled Trial 

      Kaptchuk, Ted Jack; Shaw, Jessica; Kerr, Catherine; Conboy, Lisa Ann; Kelley, John Michael; Csordas, Thomas J.; Lembo, Anthony J.; Jacobson, Eric Emil (Springer Verlag, 2009)
      Patients in the placebo arms of randomized controlled trials (RCT) often experience positive changes from baseline. While multiple theories concerning such “placebo effects” exist, peculiarly, none has been informed by ...
    • Participants' Experiences of Being Debriefed to Placebo Allocation in a Clinical Trial 

      Bishop, F. L.; Jacobson, Eric Emil; Shaw, J.; Kaptchuk, Ted Jack (SAGE Publications, 2012)
      Participants in placebo-controlled clinical trials give informed consent to be randomized to verum or placebo. However, researchers rarely tell participants which treatment they actually received. We interviewed four ...
    • Patient and Practitioner Influences on the Placebo Effect in Irritable Bowel Syndrome 

      Kelley, John Michael; Lembo, Anthony J.; Ablon, John Stuart; Villanueva, Joel J.; Conboy, Lisa Ann; Levy, Raymond Arthur; Marci, Carl David; Kerr, Catherine; Kirsch, Irving; Jacobson, Eric Emil; Riess, Helen; Kaptchuk, Ted Jack (Ovid Technologies (Wolters Kluwer Health), 2009)
      Objective: To determine whether placebo responses can be explained by characteristics of the patient, the practitioner, or their interpersonal interaction. Methods: We performed an analysis of videotape and psychometric ...
    • Placebo acupuncture as a form of ritual touch healing: A neurophenomenological model 

      Kerr, Catherine; Shaw, Jessica R.; Conboy, Lisa Ann; Kelley, John Michael; Jacobson, Eric Emil; Kaptchuk, Ted Jack (Elsevier BV, 2011)
      Evidence that placebo acupuncture is an effective treatment for chronic pain presents a puzzle: how do placebo needles appearing to patients to penetrate the body, but instead sitting on the skin’s surface in the manner ...
    • Scientific tools, fake treatments, or triggers for psychological healing: How clinical trial participants conceptualise placebos 

      Bishop, Felicity L.; Jacobson, Eric Emil; Shaw, Jessica R.; Kaptchuk, Ted Jack (Elsevier BV, 2012)
      Placebos are an essential tool in randomised clinical trials, where they are used to control for contextual healing effects. Placebos and their effects are also studied from multiple diverse perspectives, but the perspectives ...
    • Structural Integration as an Adjunct to Outpatient Rehabilitation for Chronic Nonspecific Low Back Pain: A Randomized Pilot Clinical Trial 

      Jacobson, Eric E.; Meleger, Alec L.; Bonato, Paolo; Wayne, Peter M.; Langevin, Helene M.; Kaptchuk, Ted J.; Davis, Roger B. (Hindawi Publishing Corporation, 2015)
      Structural Integration (SI) is an alternative method of manipulation and movement education. To obtain preliminary data on feasibility, effectiveness, and adverse events (AE), 46 outpatients from Boston area with chronic ...
    • A Treatment Trial of Acupuncture in IBS Patients 

      Lembo, Anthony J.; Conboy, Lisa Ann; Kelley, John Michael; Schnyer, Rosa S; McManus, Claire A; Quilty, Mary T; Kerr, Catherine; Drossman, Doug; Jacobson, Eric Emil; Davis, Roger B.; Kaptchuk, Ted Jack (Nature Publishing Group, 2009)
      Objective: To compare the effects of true and sham acupuncture in relieving symptoms of IBS. Methods: A total of 230 adult IBS patients (75% females, average age 38.4 yrs) were randomly assigned to 3 weeks of true or sham ...