Now showing items 1-2 of 2

    • Ablation of SGK1 Impairs Endothelial Cell Migration and Tube Formation Leading to Decreased Neo-Angiogenesis Following Myocardial Infarction 

      Zarrinpashneh, Elham; Poggioli, Tommaso; Sarathchandra, Padmini; Lexow, Jonas; Monassier, Laurent; Terracciano, Cesare; Lang, Florian; Damilano, Federico; Zhou, Jessica Q.; Rosenzweig, Anthony; Rosenthal, Nadia; Santini, Maria Paola (Public Library of Science, 2013)
      Serum and glucocorticoid inducible kinase 1 (SGK1) plays a pivotal role in early angiogenesis during embryonic development. In this study, we sought to define the SGK1 downstream signalling pathways in the adult heart and ...
    • Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines 

      Lauriol, Jessica; Cabrera, Janel Rodriguez; Roy, Ashbeel; Keith, Kimberly; Hough, Sara M.; Damilano, Federico; Wang, Bonnie; Segarra, Gabriel C.; Flessa, Meaghan E.; Miller, Lauren E.; Das, Saumya; Bronson, Roderick Terry; Lee, Kyu-Ho; Kontaridis, Maria Irene (American Society for Clinical Investigation, 2016)
      Hypertrophic cardiomyopathy is a common cause of mortality in congenital heart disease (CHD). Many gene abnormalities are associated with cardiac hypertrophy, but their function in cardiac development is not well understood. ...