Browsing by Author "Schwab, Joseph"
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Differences in sex distribution, anatomic location and MR imaging appearance of pediatric compared to adult chordomas
Sebro, Ronnie; DeLaney, Thomas; Hornicek, Francis; Schwab, Joseph; Choy, Edwin; Nielsen, G. Petur; Rosenthal, Daniel I. (BioMed Central, 2016)Background: Chordomas are rare malignancies that primarily affect adults, but also rarely affect pediatric patients. We compared the imaging appearance, demographic and anatomic distributions of adult and pediatric chordomas ... -
The Discrepancy between Patient and Clinician Reported Function in Extremity Bone Metastases
Janssen, Stein J.; van Rein, Eva A. J.; Paulino Pereira, Nuno Rui; Raskin, Kevin A.; Ferrone, Marco L.; Hornicek, Francis J.; Lozano-Calderon, Santiago A.; Schwab, Joseph H. (Hindawi Publishing Corporation, 2016)Background:. The Musculoskeletal Tumor Society (MSTS) scoring system measures function and is commonly used but criticized because it was developed to be completed by the clinician and not by the patient. We therefore ... -
The Identification of Prognostic Factors and Survival Statistics of Conventional Central Chondrosarcoma
Nota, Sjoerd P. F. T.; Braun, Yvonne; Schwab, Joseph H.; van Dijk, C. Niek; Bramer, Jos A. M. (Hindawi Publishing Corporation, 2015)Introduction:. Chondrosarcomas are malignant bone tumors that are characterized by the production of chondroid tissue. Since radiation therapy and chemotherapy have limited effect on chondrosarcoma, treatment of most ... -
Intraosseous Synovial Sarcoma of the Proximal Tibia
Beck, Sarah E.; Nielsen, Gunnlaugur Petur; Raskin, Kevin Andrew; Schwab, Joseph H. (Hindawi Publishing Corporation, 2011)Synovial Sarcoma is a malignant mesenchymal tumor that comprises 5–10% of all soft tissue sarcomas. The mean age of onset is thirty years old. Intraosseous presentation is very rare and has only been documented a few times. ... -
Recurrent Chromosomal Copy Number Alterations in Sporadic Chordomas
Le, Long Phi; Nielsen, Gunnlaugur Petur; Rosenberg, Andrew Eric; Thomas, Dafydd; Batten, Julie M.; Deshpande, Vikram; Schwab, Joseph H; Duan, Zhenfeng; Xavier, Ramnik; Hornicek, Francis John; Iafrate, Anthony John (Public Library of Science, 2011)The molecular events in chordoma pathogenesis have not been fully delineated, particularly with respect to copy number changes. Understanding copy number alterations in chordoma may reveal critical disease mechanisms that ...