Browsing by Author "Cristofaro, Vivian"
Now showing items 1-4 of 4
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The impact of discrete modes of spinal cord injury on bladder muscle contractility
Seth, Abhishek; Chung, Yeun Goo; Kim, Daniel; Ramachandran, Aruna; Cristofaro, Vivian; Gomez III, Pablo; Tu, Duong D; Huang, Lin; Benowitz, Larry Ira; Di Vizio, Dolores; Sullivan, Maryrose P.; Adam, Rosalyn Mare (BioMed Central, 2013)Background: Prior studies have compared the effect of spinal cord injury elicited using distinct approaches on motor and visceral function. However, the impact of such discrete modes of injury specifically on bladder muscle ... -
Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes
Wang, Zongwei; Cheng, Zhiyong; Cristofaro, Vivian; Li, Jijun; Xiao, Xingyuan; Gomez, Pablo; Ge, Rongbin; Gong, Edward; Strle, Klemen; Sullivan, Maryrose P.; Adam, Rosalyn M.; White, Morris F.; Olumi, Aria F. (American Diabetes Association, 2012)Diabetic bladder dysfunction (DBD) is common and affects 80% of diabetic patients. However, the molecular mechanisms underlying DBD remain elusive because of a lack of appropriate animal models. We demonstrate DBD in a ... -
Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury
Chung, Yeun Goo; Seth, Abhishek; Doyle, Claire; Franck, Debra; Kim, Daniel; Cristofaro, Vivian; Benowitz, Larry I.; Tu, Duong D.; Estrada, Carlos R.; Mauney, Joshua R.; Sullivan, Maryrose P.; Adam, Rosalyn M. (Public Library of Science, 2015)Neurogenic detrusor overactivity and the associated loss of bladder control are among the most challenging complications of spinal cord injury (SCI). Anticholinergic agents are the mainstay for medical treatment of detrusor ... -
Myosin Va Plays a Role in Nitrergic Smooth Muscle Relaxation in Gastric Fundus and Corpora Cavernosa of Penis
Chaudhury, Arun; Cristofaro, Vivian; Carew, Josephine A.; Goyal, Raj K.; Sullivan, Maryrose P. (Public Library of Science, 2014)The intracellular motor protein myosin Va is involved in nitrergic neurotransmission possibly by trafficking of neuronal nitric oxide synthase (nNOS) within the nerve terminals. In this study, we examined the role of myosin ...