Now showing items 1-9 of 9

    • Analysis of 14 BAC Sequences from the Aedes Aegypti Genome: A Benchmark for Genome Annotation and Assembly 

      Lobo, Neil F; Campbell, Kathy S; Thaner, Daniel; deBruyn, Becky; Koo, Hean; Gelbart, William Martin; Loftus, Brendan J; Severson, David W; Collins, Frank H (BioMed Central, 2007)
      In order to provide a set of manually curated and annotated sequences from the Aedes aegypti genome, mapped BAC clones encompassing 1.57 Mb were sequenced, assembled and manually annotated using computational gene-finding, ...
    • Annotation of the Drosophila Melanogaster Euchromatic Genome: A Systematic Review 

      Misra, Sima; Mungall, Christopher J; Campbell, Kathryn S; Hradecky, Pavel; Huang, Yanmei; Kaminker, Joshua S; Millburn, Gillian H; Prochnik, Simon E; Tupy, Jonathan L; Whitfield, Eleanor J; Bayraktaroglu, Leyla; Bettencourt, Brian R; Celniker, Susan E; de Grey, Aubrey DNJ; Drysdale, Rachel A; Harris, Nomi L; Richter, John; Shu, ShengQiang; Stapleton, Mark; Yamada, Chihiro; Ashburner, Michael; Rubin, Gerald M; Lewis, Suzanna E; Crosby, Madeline; Matthews, Beverley; Smith, Christopher D; Berman, Benjamin P; Russo, Susan; Schroeder, Andrew; Gelbart, William Martin (BioMed Central, 2002)
      The recent completion of the Drosophila melanogaster genomic sequence to high quality, and the availability of a greatly expanded set of Drosophila cDNA sequences, afforded FlyBase the opportunity to significantly improve ...
    • Automatic Categorization of Diverse Experimental Information in the Bioscience Literature 

      Fang, Ruihua; Schindelman, Gary; Auken, Kimberly Van; Fernandes, Jolene; Chen, Wen; Wang, Xiaodong; Davis, Paul; Tuli, Mary Ann; Marygold, Steven J; Millburn, Gillian; Matthews, Beverley; Zhang, Haiyan; Brown, Nick; Gelbart, William Martin; Sternberg, Paul W (BioMed Central, 2012)
      Background: Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical ...
    • The Evolution of the Anopheles 16 Genomes Project 

      Neafsey, Daniel E.; Christophides, George K.; Collins, Frank H.; Emrich, Scott J.; Fontaine, Michael C.; Gelbart, William; Hahn, Matthew W.; Howell, Paul I.; Kafatos, Fotis C.; Lawson, Daniel; Muskavitch, Marc A. T.; Waterhouse, Robert M.; Williams, Louise J.; Besansky, Nora J. (Genetics Society of America, 2013)
      We report the imminent completion of a set of reference genome assemblies for 16 species of Anopheles mosquitoes. In addition to providing a generally useful resource for comparative genomic analyses, these genome sequences ...
    • FlyBase: genomes by the dozen 

      Crosby, Madeline; Goodman, Joshua L.; Strelets, Victor B.; Zhang, Peili; Gelbart, William Martin; The FlyBase Consortium (Oxford University Press, 2006)
      FlyBase (http://flybase.org/) is the primary database of genetic and genomic data for the insect family Drosophilidae. Historically, Drosophila melanogaster has been the most extensively studied species in this family, but ...
    • FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations 

      dos Santos, Gilberto; Schroeder, Andrew J.; Goodman, Joshua L.; Strelets, Victor B.; Crosby, Madeline A.; Thurmond, Jim; Emmert, David B.; Gelbart, William M. (Oxford University Press, 2015)
      Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster, was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous Release 5 genome assembly, which had been ...
    • Inferring Genome-Scale Rearrangement Phylogeny and Ancestral Gene Order: A Drosophila Case Study 

      Bhutkar, Arjun; Gelbart, William Martin; Smith, Temple F (BioMed Central, 2007)
      A simple, fast, and biologically-inspired computational approach to infer genome-scale rearrangement phylogeny and ancestral gene order has been developed and applied to eight Drosophila genomes, providing insights into ...
    • A Simple RNA-DNA Scaffold Templates the Assembly of Monofunctional Virus-Like Particles 

      Garmann, Rees; Sportsman, Richard; Beren, Christian; Manoharan, Vinothan N.; Knobler, Charles M.; Gelbart, William (American Chemical Society (ACS), 2015)
      Using the components of a particularly well-studied plant virus, cowpea chlorotic mottle virus (CCMV), we demonstrate the synthesis of virus-like particles (VLPs) with one end of the packaged RNA extending out of the capsid ...
    • VectorBase: A Data Resource for Invertebrate Vector Genomics 

      Lawson, Daniel; Arensburger, Peter; Besansky, Nora J.; Bruggner, Robert V.; Butler, Ryan; Campbell, Kathryn S.; Christophides, George K.; Christley, Scott; Dialynas, Emmanuel; Hammond, Martin; Hill, Catherine A.; Konopinski, Nathan; Lobo, Neil F.; MacCallum, Robert M.; Madey, Greg; Megy, Karine; Redmond, Seth; Severson, David W.; Stinson, Eric O.; Topalis, Pantelis; Birney, Ewan; Louis, Christos; Collins, Frank H.; Atkinson, Peter; Meyer, Jason; Gelbart, William Martin; Kafatos, Fotis Constantine (Oxford University Press, 2009)
      VectorBase (http://www.vectorbase.org) is an NIAID-funded Bioinformatic Resource Center focused on invertebrate vectors of human pathogens. VectorBase annotates and curates vector genomes providing a web accessible integrated ...