Browsing by Author "Wolf, Maxim Y"

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    • FRESCo: finding regions of excess synonymous constraint in diverse viruses 

      Sealfon, Rachel S; Lin, Michael F; Jungreis, Irwin; Wolf, Maxim Y; Kellis, Manolis; Sabeti, Pardis C (BioMed Central, 2015)
      Background: The increasing availability of sequence data for many viruses provides power to detect regions under unusual evolutionary constraint at a high resolution. One approach leverages the synonymous substitution rate ...