Browsing by Author "McAllister, Sandra"
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The Bed and the Bugs: Interactions Between the Tumor Microenvironment and Cancer Stem Cells
Castaño, Zafira; Fillmore, Christine M.; Kim, Carla; McAllister, Sandra (Elsevier BV, 2012-10)Tumors have been increasingly recognized as organs with a complexity that approaches, and may even exceed, that of healthy tissues. When viewed from this perspective, the biology of a tumor can be understood only by studying ... -
Subclonal Cooperation Drives Metastasis by Modulating Local and Systemic Immune Microenvironments
Cristea, Simona; Kwak, Minsuk; Qin, Yuanbo; Laszewski, Tyler; Luoma, Adrienne; Marusyk, Andriy; Wagle, Nikhil; Fang, Rongxin; Polyak, Kornelia; Janiszewska, Michalina; Tabassum, Doris; Castaño, Zafira; Yamamoto, Kimiyo; Kingston, Natalie; Murphy, Katherine; Shu, Shaokun; Harper, Nicholas; Gil del Alcazar, Carlos; Alečković, Maša; Ekram, Muhammad; Cohen, Ofir; Cohen, Ofir; Wucherpfennig, Kai; Michor, Franziska; McAllister, Sandra (Springer Science and Business Media LLC, 2019-07)Most human tumours are heterogeneous, composed of cellular clones with different properties present at variable frequencies. Highly heterogeneous tumours have poor clinical outcomes, yet the underlying mechanism remains ... -
The unresolved role of systemic factors in bone metastasis
Ubellacker, Jessalyn M.; McAllister, Sandra S. (Elsevier, 2016)Systemic factors including cytokines, cell-free nucleic acids, microvesicles, and platelets are appreciated as important regulators of adenocarcinoma progression. Research findings using pre-clinical mouse models have ...