Browsing by Author "Frumin, Melissa"

Now showing items 1-20 of 22

    • Association Between Reduced Extraversion and Right Posterior Fusiform Gyrus Gray Matter Reduction in Chronic Schizophrenia 

      Onitsuka, Toshiaki; Nestor, Paul Gerard; Gurrera, Ronald Joseph; Shenton, Martha Elizabeth; Kasai, Kiyoto; Frumin, Melissa; Niznikiewicz, Margaret A.; McCarley, Robert William (American Psychiatric Publishing, 2005)
      Objective: The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia. Method: Male patients ...

    • Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study 

      Kubicki, Marek R.; Westin, Carl-Fredrik; Nestor, Paul Gerard; Wible, Cynthia Gayle; Frumin, Melissa; Maier, Stephan Ernst; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2003)
      Background: Evidence suggests that a disruption in limbic system network integrity and, in particular, the cingulate gyrus (CG), may play a role in the pathophysiology of schizophrenia; however, the cingulum bundle (CB), ...

    • Diffusion Tensor Imaging and Its Application to Neuropsychiatric Disorders 

      Kubicki, Marek R.; Westin, Carl-Fredrik; Maier, Stephan Ernst; Mamata, Hatsuho; Frumin, Melissa; Ersner-Hershfield, Hal; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (Ovid Technologies (Wolters Kluwer Health), 2002)
      Magnetic resonance diffusion tensor imaging (DTI) is a new technique that can be used to visualize and measure the diffusion of water in brain tissue; it is particularly useful for evaluating white matter abnormalities. ...

    • Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia 

      Nestor, Paul Gerard; Onitsuka, Toshiaki; Gurrera, Ronald Joseph; Niznikiewicz, Margaret A.; Frumin, Melissa; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2007)
      We sought to identify the functional correlates of reduced magnetic resonance imaging (MRI) volumes of the superior temporal gyrus (STG) and the fusiform gyrus (FG) in patients with chronic schizophrenia. MRI volumes, ...

    • DTI and MTR abnormalities in schizophrenia: Analysis of white matter integrity 

      Kubicki, Marek R.; Park, H.; Westin, Carl-Fredrik; Nestor, Paul Gerard; Mulkern, Robert Vincent; Maier, Stephan Ernst; Niznikiewicz, Margaret A.; Connor, E.E.; Levitt, James Jonathan; Frumin, Melissa; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2005)
      Diffusion tensor imaging (DTI) studies in schizophrenia demonstrate lower anisotropic diffusion within white matter due either to loss of coherence of white matter fiber tracts, to changes in the number and/or density of ...

    • Fornix Integrity and Hippocampal Volume in Male Schizophrenic Patients 

      Kuroki, Noriomi; Kubicki, Marek R.; Nestor, Paul Gerard; Salisbury, Dean F.; Park, Hae-Jeong; Levitt, James Jonathan; Woolston, Sophie; Frumin, Melissa; Niznikiewicz, Margaret A.; Westin, Carl-Fredrik; Maier, Stephan Ernst; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2006)
      Background: The hippocampus has been shown to be abnormal in schizophrenia. The fornix is one of the main fiber tracts connecting the hippocampus with other brain regions. Few studies have evaluated the fornix in schizophrenia, ...

    • Functional and Structural Deficits in Brain Regions Subserving Face Perception in Schizophrenia 

      Onitsuka, Toshiaki; Niznikiewicz, Margaret A.; Spencer, Kevin M.; Frumin, Melissa; Kuroki, Noriomi; Lucia, Lisa C.; Shenton, Martha Elizabeth; McCarley, Robert William (American Psychiatric Publishing, 2006)
      Objective: Schizophrenia impairs many cognitive functions, including face perception. Veridical face perception is critical for social interaction, including distinguishing friend from foe and familiar from unfamiliar ...

    • Middle and Inferior Temporal Gyrus Gray Matter Volume Abnormalities in Chronic Schizophrenia: An MRI Study 

      Onitsuka, Toshiaki; Shenton, Martha Elizabeth; Salisbury, Dean F.; Dickey, Chandlee C.; Kasai, Kiyoto; Toner, Sarah K.; Frumin, Melissa; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William (American Psychiatric Publishing, 2004)
      Objective: The middle temporal gyrus and inferior temporal gyrus subserve language and semantic memory processing, visual perception, and multimodal sensory integration. Functional deficits in these cognitive processes ...

    • MRI anatomy of schizophrenia 

      McCarley, Robert William; Wible, Cynthia Gayle; Frumin, Melissa; Hirayasu, Yoshio; Levitt, James Jonathan; Fischer, Iris A.; Shenton, Martha Elizabeth (Elsevier BV, 1999)
      Structural magnetic resonance imaging (MRI) data have provided much evidence in support of our current view that schizophrenia is a brain disorder with altered brain structure, and consequently involving more than a simple ...

    • A MRI study of fusiform gyrus in schizotypal personality disorder 

      Dickey, Chandlee C.; McCarley, Robert William; Voglmaier, Martina M.; Niznikiewicz, Margaret A.; Seidman, Larry Joel; Frumin, Melissa; Toner, Sarah; Demeo, Susan; Shenton, Martha Elizabeth (Elsevier BV, 2003)
      The fusiform gyrus is important for face and object recognition, is abnormal in schizophrenia, but has not been studied in schizotypal personality disorder (SPD). Thin-slice MR images showed no differences, either in right, ...

    • An MRI Study of Superior Temporal Gyrus Volume in Women With Schizotypal Personality Disorder 

      Dickey, Chandlee C.; McCarley, Robert William; Voglmaier, Martina M.; Niznikiewicz, Margaret A.; Seidman, Larry Joel; Demeo, Susan; Frumin, Melissa; Shenton, Martha Elizabeth (American Psychiatric Publishing, 2003)
      Objective: An abnormal superior temporal gyrus has figured prominently in schizophrenia research, and left superior temporal gyrus volume has been shown to be smaller in male subjects with schizotypal personality disorder. ...

    • Neural synchrony indexes disordered perception and cognition in schizophrenia 

      Spencer, Kevin M.; Nestor, Paul Gerard; Perlmutter, R.; Niznikiewicz, Margaret A.; Klump, M. C.; Frumin, Melissa; Shenton, Martha Elizabeth; McCarley, Robert William (Proceedings of the National Academy of Sciences, 2004)
      Current views of schizophrenia suggest that it results from abnormalities in neural circuitry, but empirical evidence in the millisecond range of neural activity has been difficult to obtain. In pursuit of relevant evidence, ...

    • Neuropsychological Correlates of Diffusion Tensor Imaging in Schizophrenia. 

      Nestor, Paul Gerard; Kubicki, Marek R.; Gurrera, Ronald Joseph; Niznikiewicz, Margaret A.; Frumin, Melissa; McCarley, Robert William; Shenton, Martha Elizabeth (American Psychological Association (APA), 2004)
      Patients with schizophrenia (n = 41) and healthy comparison participants (n = 46) completed neuropsychological measures of intelligence, memory, and executive function. A subset of each group also completed magnetic resonance ...

    • Occipital lobe gray matter volume in male patients with chronic schizophrenia: A quantitative MRI study 

      Onitsuka, Toshiaki; McCarley, Robert William; Kuroki, Noriomi; Dickey, Chandlee C.; Kubicki, Marek R.; Demeo, Susan S.; Frumin, Melissa; Kikinis, Ron; Jolesz, Ferenc A.; Shenton, Martha Elizabeth (Elsevier BV, 2007)
      Schizophrenia is characterized by deficits in cognition as well as visual perception. There have, however, been few magnetic resonance imaging (MRI) studies of the occipital lobe as an anatomically defined region of interest ...

    • Planum Temporale and Heschl Gyrus Volume Reduction in Schizophrenia 

      Hirayasu, Yoshio; McCarley, Robert William; Salisbury, Dean F.; Tanaka, Shin; Soo Kwon, Jun; Frumin, Melissa; Snyderman, Danielle; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; Shenton, Martha Elizabeth (American Medical Association, 2000)
      Background: Magnetic resonance imaging studies in schizophrenia have revealed abnormalities in temporal lobe structures, including the superior temporal gyrus. More specifically, abnormalities have been reported in the ...

    • Processing sentence context in women with schizotypal personality disorder: An ERP study 

      Niznikiewicz, Margaret A.; Friedman, Michelle; Shenton, Martha Elizabeth; Voglmaier, Martina M.; Nestor, Paul Gerard; Frumin, Melissa; Seidman, Larry Joel; Sutton, Johnathan; McCarley, Robert William (Wiley-Blackwell, 2004)
      Accumulating evidence suggests that schizophrenic patients do not use context efficiently. Also, studies suggest similarities in clinical and cognitive profiles between schizophrenic and schizotypal personality disorder ...

    • A review of MRI findings in schizophrenia 

      Shenton, Martha Elizabeth; Dickey, Chandlee C.; Frumin, Melissa; McCarley, Robert William (Elsevier BV, 2001)
      After more than 100 years of research, the neuropathology of schizophrenia remains unknown and this is despite the fact that both Kraepelin (1919/1971: Kraepelin,E., 1919/1971. Dementia praecox. Churchill Livingston Inc., ...

    • Semantic Dysfunction in Women With Schizotypal Personality Disorder 

      Niznikiewicz, Margaret A.; Shenton, Martha Elizabeth; Voglmaier, Martina M.; Nestor, Paul Gerard; Dickey, Chandlee C.; Frumin, Melissa; Seidman, Larry Joel; Allen, Christopher G.; McCarley, Robert William (American Psychiatric Publishing, 2002)
      Objective: This study examined whether early or late processes in semantic networks were abnormal in women with a diagnosis of schizotypal personality disorder. The N400 component of the EEG event-related potentials was ...

    • Shape Differences in the Corpus Callosum in First-Episode Schizophrenia and First-Episode Psychotic Affective Disorder 

      Frumin, Melissa; Golland, Polina; Kikinis, Ron; Hirayasu, Yoshio; Salisbury, Dean F.; Hennen, John; Dickey, Chandlee C.; Anderson, Mark Allen; Jolesz, Ferenc A.; Grimson, W. Eric L.; McCarley, Robert William; Shenton, Martha Elizabeth (American Psychiatric Publishing, 2002)
      Objective: The corpus callosum, the largest white matter tract in the brain, is a midline structure associated with the formation of the hippocampus, septum pellucidum, and cingulate cortex, which have been implicated in ...

    • Smaller Left Heschl’s Gyrus Volume in Patients With Schizotypal Personality Disorder 

      Dickey, Chandlee C.; McCarley, Robert William; Voglmaier, Martina M.; Frumin, Melissa; Niznikiewicz, Margaret A.; Hirayasu, Yoshio; Fraone, Stephanie; Seidman, Larry Joel; Shenton, Martha Elizabeth (American Psychiatric Publishing, 2002)
      Objective: Individuals with schizophrenia spectrum disorders evince similar genetic, neurotransmitter, neuropsychological, electrophysiological, and structural abnormalities. Magnetic resonance imaging (MRI) studies have ...