Browsing by Author "Fernandez, Marty"
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Sequential Proteolysis by γ-Secretase and Its Implications for Alzheimer’s Disease
Fernandez, Marty (2015-05-20)The production and aggregation of the amyloid β-peptide (Aβ) is thought to play a central role in Alzheimer’s disease (AD) pathogenesis. The presenilin (PS)-containing γ-secretase complex cleaves the amyloid β-protein ...