Browsing by Author "Plachetka, Annette"

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    • Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain 

      Riddle, Nicole C.; Jung, Youngsook; Gu, Tingting; Alekseyenko, Artyom A.; Asker, Dalal; Gui, Hongxing; Kharchenko, Peter Vasili; Minoda, Aki; Plachetka, Annette; Schwartz, Yuri B.; Tolstorukov, Michael Y.; Kuroda, Mitzi I.; Pirrotta, Vincenzo; Karpen, Gary H.; Park, Peter J.; Elgin, Sarah C. R. (Public Library of Science, 2012)
      Chromatin environments differ greatly within a eukaryotic genome, depending on expression state, chromosomal location, and nuclear position. In genomic regions characterized by high repeat content and high gene density, ...

    • Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context 

      Alekseyenko, Artyom A.; Gelbart, Marnie; Tolstorukov, Michael Y.; Gorchakov, Andrey A.; Larschan, Erica; Gu, Tingting; Minoda, Aki; Riddle, Nicole C.; Schwartz, Yuri B.; Elgin, Sarah C. R.; Karpen, Gary H.; Pirrotta, Vincenzo; Ho, Joshua Wing Kei; Peng, Shouyong; Plachetka, Annette; Kharchenko, Peter Vasili; Jung, Youngsook; Kuroda, Mitzi I.; Park, Peter J. (Public Library of Science, 2012)
      The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent ...