Browsing by Author "Bellinger, David"

Now showing items 1-20 of 45

    • Anemia of Inflammation Is Related to Cognitive Impairment among Children in Leyte, The Philippines 

      Olson, Courtney L.; Acosta, Luz P.; Hochberg, Natasha S.; Olveda, Remigio M.; Jiz, Mario; McGarvey, Stephen T.; Kurtis, Jonathan D.; Bellinger, David C.; Friedman, Jennifer (Public Library of Science, 2009)
      Background: Many studies have addressed the relationship between iron deficiency anemia (IDA) and cognitive impairment, but none have evaluated the role of non-iron deficiency anemia (NIDA). One of the main causes of NIDA ...

    • Arsenic, Lead and Manganese as Risk Factors for Child and Maternal Neurotoxicity 

      Tauheed, Jannah (2016-05-07)
      Metals such as arsenic, lead and manganese are naturally occurring elements readily found in the earth’s crust. Numerous studies have shown that these metals can be neurotoxic though the exact mechanism remains unknown. ...

    • Association of lifetime exposure to fluoride and cognitive functions in Chinese children: A pilot study 

      Choi, Anna L.; Zhang, Ying; Sun, Guifan; Bellinger, David C; Wang, Kanglin; Yang, Xiao Jing; Li, Jin Shu; Zheng, Quanmei; Fu, Yuanli; Grandjean, Philippe (Elsevier BV, 2015)
      Background A systematic review and meta-analysis of published studies on developmental fluoride neurotoxicity support the hypothesis that exposure to elevated concentrations of fluoride in water is neurotoxic during ...

    • Associations between cadmium exposure and neurocognitive test scores in a cross-sectional study of US adults 

      Ciesielski, Timothy; Bellinger, David C.; Schwartz, Joel David; Hauser, Russ B.; Wright, Robert O. (BioMed Central, 2013)
      Background: Low-level environmental cadmium exposure and neurotoxicity has not been well studied in adults. Our goal was to evaluate associations between neurocognitive exam scores and a biomarker of cumulative cadmium ...

    • Associations between Prenatal Exposure to Black Carbon and Memory Domains in Urban Children: Modification by Sex and Prenatal Stress 

      Cowell, Whitney J.; Bellinger, David C.; Coull, Brent A.; Gennings, Chris; Wright, Robert O.; Wright, Rosalind J. (Public Library of Science, 2015)
      Background: Whether fetal neurodevelopment is disrupted by traffic-related air pollution is uncertain. Animal studies suggest that chemical and non-chemical stressors interact to impact neurodevelopment, and that this ...

    • Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment 

      Henn, Birgit Claus; Schnaas, Lourdes; Lamadrid-Figueroa, Héctor; Hernández-Avila, Mauricio; Hu, Howard; Téllez-Rojo, Martha María; Ettinger, Adrienne S; Schwartz, Joel David; Amarasiriwardena, Chitra J.; Bellinger, David C.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2011)
      Background: Most toxicologic studies focus on a single agent, although this does not reflect real-world scenarios in which humans are exposed to multiple chemicals. Objectives: We prospectively studied manganese–lead ...

    • Blood Lead Levels and Major Depressive Disorder, Panic Disorder, and Generalized Anxiety Disorder in US Young Adults 

      Bouchard, Maryse F.; Bellinger, David C; Weuve, Jennifer; Matthews-Bellinger, Julia; Gilman, Stephen Edward; Wright, Robert O.; Schwartz, Joel David; Weisskopf, Marc G. (American Medical Association (AMA), 2009)
      CONTEXT: Lead is a ubiquitous neurotoxicant, and adverse cognitive and behavioral effects are well-documented in children and occupationally exposed adults but not in adults with low environmental exposure. OBJECTIVE: To ...

    • Cadmium Exposure and Neurodevelopmental Outcomes in U.S. Children 

      Ciesielski, Timothy; Weuve, Jennifer Lynn; Bellinger, David C.; Schwartz, Joel David; Lanphear, Bruce; Wright, Robert O. (National Institute of Environmental Health Sciences, 2012)
      Background: Low-level environmental cadmium exposure in children may be associated with adverse neurodevelopmental outcomes. Objective: Our aim was to evaluate associations between urinary cadmium concentration and reported ...

    • A Child with Chronic Manganese Exposure from Drinking Water 

      Woolf, Alan David; Wright, Robert O.; Amarasiriwardena, Chitra J.; Bellinger, David C. (U.S. Department of Health and Human Services & National Institute of Environmental Health Sciences, 2002)
      The patient's family bought a home in a suburb, but the proximity of the house to wetlands and its distance from the town water main prohibited connecting the house to town water. The family had a well drilled and they ...

    • Contaminated Turmeric Is a Potential Source of Lead Exposure for Children in Rural Bangladesh 

      Gleason, Kelsey; Shine, James P.; Shobnam, Nadia; Rokoff, Lisa B.; Suchanda, Hafiza Sultana; Ibne Hasan, Md Omar Sharif; Mostofa, Golam; Amarasiriwardena, Chitra; Quamruzzaman, Quazi; Rahman, Mahmuder; Kile, Molly L.; Bellinger, David C.; Christiani, David C.; Wright, Robert O.; Mazumdar, Maitreyi (Hindawi Publishing Corporation, 2014)
      Background. During the conduct of a cohort study intended to study the associations between mixed metal exposures and child health outcomes, we found that 78% of 309 children aged 20–40 months evaluated in the Munshiganj ...

    • Dental amalgam restorations and children’s neuropsychological function: The New England Children’s Amalgam Trial 

      Bellinger, David C.; Daniel, David; Trachtenberg, Felicia; Tavares, Mary Angela; McKinlay, Sonja (National Institute of Environmental Health Sciences, 2006)
      Background: A concern persists that children’s exposure to mercury vapor from dental amalgams produces neurotoxicity. Objective: Our goal was to compare the neuropsychological function of children, without prior exposure ...

    • Development and validation of an early childhood development scale for use in low-resourced settings 

      McCoy, Dana Charles; Sudfeld, Christopher Robert; Bellinger, David C; Muhihi, Alfa; Ashery, Geofrey; Weary, Taylor Evans; Fawzi, Wafaie W.; Fink, Gunther (Springer Nature, 2017)
      Background:Low-cost, cross-culturally comparable measures of the motor, cognitive, and socioemotional skills of children under 3 years remain scarce. In the present paper, we aim to develop a new caregiver-reported early ...

    • Dose–Response Relationship of Prenatal Mercury Exposure and IQ: An Integrative Analysis of Epidemiologic Data 

      Axelrad, Daniel A.; Bellinger, David C.; Ryan, Louise Marie; Woodruff, Tracey J. (National Institute of Environmental Health Sciences, 2007)
      Background: Prenatal exposure to mercury has been associated with adverse childhood neurologic outcomes in epidemiologic studies. Dose–response information for this relationship is useful for estimating benefits of reduced ...

    • Effect of breast milk lead on infant blood lead levels at 1 month of age 

      Ettinger, Adrienne S; Téllez-Rojo, Martha María; Amarasiriwardena, Chitra J.; Bellinger, David C.; Peterson, Karen E.; Schwartz, Joel David; Hu, Howard; Hernández-Avila, Mauricio (National Institue of Environmental Health Sciences, 2004)
      Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard from mothers with ...

    • Environment and Brain Development: Challenges in the Global Context 

      Julvez, Jordi; Paus, Tomas; Bellinger, David C; Eskenazi, Brenda; Tiemeier, Henning; Pearce, Neil; Ritz, Beate; White, Tonya; Ramchandani, Paul; Gispert, Juan; Desrivières, Sylvane; Brouwer, Rachel; Boucher, Olivier; Alemany, Silvia; López-Vicente, Mónica; Suades-González, Elisabeth; Forns, Joan; Grandjean, Philippe; Sunyer, Jordi (S. Karger AG, 2015)

    • Fetal Lead Exposure at Each Stage of Pregnancy as a Predictor of Infant Mental Development 

      Hu, Howard; Téllez-Rojo, Martha María; Lamadrid-Figueroa, Héctor; Schnaas, Lourdes; Mercado-García, Adriana; Hernández-Avila, Mauricio; Bellinger, David C.; Smith, Donald; Ettinger, Adrienne S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2006)
      Background: The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. Objective: We ...

    • Hair Manganese and Hyperactive Behaviors: Pilot Study of School-Age Children Exposed through Tap Water 

      Bouchard, Maryse; Laforest, François; Vandelac, Louise; Bellinger, David C.; Mergler, Donna (National Institute of Environmental Health Sciences, 2006)
      Background: Neurotoxic effects are known to occur with inhalation of manganese particulates, but very few data are available on exposure to Mn in water. We undertook a pilot study in a community in Québec (Canada) where ...

    • Lead Exposure and Behavior Among Young Children in Chennai, India 

      Roy, Ananya; Bellinger, David C.; Hu, Howard; Schwartz, Joel David; Ettinger, Adrienne S; Wright, Robert O.; Bouchard, Maryse; Palaniappan, Kavitha; Balakrishnan, Kalpana (National Institute of Environmental Health Sciences, 2009)
      Background: Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. Objective: We evaluated the ...

    • Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives 

      Grandjean, Philippe; Barouki, Robert; Bellinger, David C; Casteleyn, Ludwine; Chadwick, Lisa H.; Cordier, Sylvaine; Etzel, Ruth A.; Gray, Kimberly A.; Ha, Eun-Hee; Junien, Claudine; Karagas, Margaret; Kawamoto, Toshihiro; Paige Lawrence, B.; Perera, Frederica P.; Prins, Gail S.; Puga, Alvaro; Rosenfeld, Cheryl S.; Sherr, David H.; Sly, Peter D.; Suk, William; Sun, Qi; Toppari, Jorma; van den Hazel, Peter; Walker, Cheryl L.; Heindel, Jerrold J. (The Endocrine Society, 2015)
      The Developmental Origins of Health and Disease (DOHaD) paradigm is one of the most rapidly expanding areas of biomedical research. Environmental stressors that can impact on DOHaD encompass a variety of environmental and ...

    • Low-level Environmental Lead Exposure and Children’s Intellectual Function: An International Pooled Analysis 

      Lanphear, Bruce P.; Hornung, Richard; Khoury, Jane; Yolton, Kimberly; Baghurst, Peter; Canfield, Richard L.; Dietrich, Kim N.; Bornschein, Robert; Greene, Tom; Needleman, Herbert L.; Schnaas, Lourdes; Wasserman, Gail; Graziano, Joseph; Roberts, Russell; Bellinger, David C.; Rothenberg, Stephen J. (National Institue of Environmental Health Sciences, 2005)
      Lead is a confirmed neurotoxin, but questions remain about lead-associated intellectual deficits at blood lead levels < 10 μg/dL and whether lower exposures are, for a given change in exposure, associated with greater ...