Now showing items 1-2 of 2

    • Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication 

      Annes, J. P.; Ryu, J. H.; Lam, K.; Carolan, Peter Joseph; Utz, K.; Hollister-Lock, J.; Anthony, Anthony; Rubin, Lee; Weir, Gordon Campbell; Melton, Douglas A. (Proceedings of the National Academy of Sciences, 2012)
      Diabetes is a pathological condition characterized by relative insulin deficiency, persistent hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. One therapeutic strategy is to amplify insulin-secretion ...
    • New findings in pancreatic and intestinal endocrine development to advance regenerative medicine 

      Carolan, Peter Joseph; Melton, Douglas A. (Ovid Technologies (Wolters Kluwer Health), 2013)
      Purpose of review: We highlight some of the major recent advances that have been made towards understanding the mechanisms that control endocrine differentiation and cell identity in the pancreas and intestine. Recent ...