Now showing items 1-3 of 3

    • ACME: Automated Cell Morphology Extractor for Comprehensive Reconstruction of Cell Membranes 

      Mosaliganti, Kishore Rao; Noche, Ramil; Xiong, Fengzhu; Swinburne, Ian A; Megason, Sean G. (Public Library of Science, 2012)
      The quantification of cell shape, cell migration, and cell rearrangements is important for addressing classical questions in developmental biology such as patterning and tissue morphogenesis. Time-lapse microscopic imaging ...
    • Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells 

      Brodsky, Alexander S; Meyer, Clifford; Swinburne, Ian A; Hall, Giles; Keenan, Benjamin J; Liu, Xiaole Shirley; Fox, Edward Alvin; Silver, Pamela A. (BioMed Central, 2005)
      Background: Transcription by RNA polymerase II is regulated at many steps including initiation, promoter release, elongation and termination. Accumulation of RNA polymerase II at particular locations across genes can be ...
    • Improved Long-Term Imaging of Embryos with Genetically Encoded α-Bungarotoxin 

      Swinburne, Ian A.; Mosaliganti, Kishore R.; Green, Amelia A.; Megason, Sean G. (Public Library of Science, 2015)
      Rapid advances in microscopy and genetic labeling strategies have created new opportunities for time-lapse imaging of embryonic development. However, methods for immobilizing embryos for long periods while maintaining ...