Now showing items 1-3 of 3

    • Analysis of Multiple Sarcoma Expression Datasets: Implications for Classification, Oncogenic Pathway Activation and Chemotherapy Resistance 

      Konstantinopoulos, Panagiotis; Fountzilas, Elena; Goldsmith, Jeffrey David; Bhasin, Manoj; Pillay, Kamana; Francoeur, Nancy; Libermann, Towia Aron; Gebhardt, Mark Clyde; Spentzos, Dimitrios (Public Library of Science, 2010)
      Background: Diagnosis of soft tissue sarcomas (STS) is challenging. Many remain unclassified (not-otherwise-specified, NOS) or grouped in controversial categories such as malignant fibrous histiocytoma (MFH), with unclear ...
    • A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study 

      Fountzilas, Elena; Kelly, Andrew D; Perez-Atayde, Antonio Rafael; Goldsmith, Jeffrey David; Konstantinopoulos, Panagiotis; Francoeur, Nancy; Correll, Mick; Rubio, Renee; Hu, Lan; Gebhardt, Mark Clyde; Quackenbush, John; Spentzos, Dimitrios (BioMed Central, 2012)
      Background: MicroRNAs (miRNAs) are nucleic acid regulators of many human mRNAs, and are associated with many tumorigenic processes. miRNA expression levels have been used in profiling studies, but some evidence suggests ...
    • MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32 

      Kelly, Andrew D; Haibe-Kains, Benjamin; Janeway, Katherine A; Hill, Katherine E; Howe, Eleanor; Goldsmith, Jeffrey; Kurek, Kyle; Perez-Atayde, Antonio R; Francoeur, Nancy; Fan, Jian-Bing; April, Craig; Schneider, Hal; Gebhardt, Mark C; Culhane, Aedin; Quackenbush, John; Spentzos, Dimitrios (BioMed Central, 2013)
      Background: Although microRNAs (miRNAs) are implicated in osteosarcoma biology and chemoresponse, miRNA prognostic models are still needed, particularly because prognosis is imperfectly correlated with chemoresponse. ...