Browsing by Author "Chu, Renxin"
Now showing items 1-7 of 7
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Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis
Tauhid, Shahamat; Chu, Renxin; Sasane, Rahul; Glanz, Bonnie I.; Neema, Mohit; Miller, Jennifer R.; Kim, Gloria; Signorovitch, James E.; Healy, Brian C.; Chitnis, Tanuja; Weiner, Howard L.; Bakshi, Rohit (Springer Berlin Heidelberg, 2015)Multiple sclerosis (MS) commonly affects occupational function. We investigated the link between brain MRI and employment status. Patients with MS (n = 100) completed a Work Productivity and Activity Impairment (WPAI) ... -
The Contribution of Cortical Lesions to a Composite MRI Scale of Disease Severity in Multiple Sclerosis
Yousuf, Fawad; Kim, Gloria; Tauhid, Shahamat; Glanz, Bonnie I.; Chu, Renxin; Tummala, Subhash; Healy, Brian C.; Bakshi, Rohit (Frontiers Media S.A., 2016)Objective: To test a new version of the Magnetic Resonance Disease Severity Scale (v.3 = MRDSS3) for multiple sclerosis (MS), incorporating cortical gray matter lesions (CLs) from 3T magnetic resonance imaging (MRI). ... -
The Effect of Dimethyl Fumarate on Cerebral Gray Matter Atrophy in Multiple Sclerosis
Dupuy, Sheena L.; Tauhid, Shahamat; Hurwitz, Shelley; Chu, Renxin; Yousuf, Fawad; Bakshi, Rohit (Springer Healthcare, 2016)Introduction: The objective of this pilot study was to compare cerebral gray matter (GM) atrophy over 1 year in patients starting dimethyl fumarate (DMF) for multiple sclerosis (MS) to that of patients on no disease-modifying ... -
MRI detection of hypointense brain lesions in patients with multiple sclerosis: T1 spin-echo vs. gradient-echo
Dupuy, Sheena; Tauhid, Shahamat Syed; Kim, Gloria; Chu, Renxin; Tummala, Subhash; Hurwitz, Shelley; Bakshi, Rohit (Elsevier BV, 2015)Objective Compare T1 spin-echo (T1SE) and T1 gradient-echo (T1GE) sequences in detecting hypointense brain lesions in multiple sclerosis (MS). Background Chronic hypointense lesions on T1SE MRI scans are a surrogate ... -
Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis
Bakshi, Rohit; Yeste, A; Patel, B.; Tauhid, Shahamat Syed; Tummala, Subhash; Rahbari, R.; Chu, Renxin; Regev, Keren; Kivisakk, Pia; Weiner, Howard Lee; Quintana, Francisco Javier (Ovid Technologies (Wolters Kluwer Health), 2016)Objective: To determine whether peripheral immune responses as measured by serum antigen arrays are linked to cerebral MRI measures of disease severity in multiple sclerosis (MS). Methods: In this cross-sectional study, ... -
T1- vs. T2-based MRI measures of spinal cord volume in healthy subjects and patients with multiple sclerosis
Kim, Gloria; Khalid, Fariha; Oommen, Vinit V.; Tauhid, Shahamat; Chu, Renxin; Horsfield, Mark A.; Healy, Brian C.; Bakshi, Rohit (BioMed Central, 2015)Background: The reliable and efficient measurement of spinal cord atrophy is of growing interest in monitoring disease progression in multiple sclerosis (MS). Methods: We compared T1- and T2-weighted MRI for measuring ... -
Whole Brain Volume Measured from 1.5T versus 3T MRI in Healthy Subjects and Patients with Multiple Sclerosis
Chu, Renxin; Tauhid, Shahamat Syed; Glanz, Bonnie; Healy, Brian Curran; Kim, Gloria; Oommen, Vinit V.; Khalid, Fariha; Neema, Mohit; Bakshi, Rohit (Wiley-Blackwell, 2015)Background: Whole brain atrophy is a putative outcome measure in monitoring relapsing-remitting multiple sclerosis (RRMS). With the ongoing MRI transformation from 1.5T to 3T, there is an unmet need to calibrate this change. ...