Now showing items 1-2 of 2

    • Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships 

      McHardy, Ian H; Goudarzi, Maryam; Tong, Maomeng; Ruegger, Paul M; Schwager, Emma; Weger, John R; Graeber, Thomas G; Sonnenburg, Justin L; Horvath, Steve; Huttenhower, Curtis; McGovern, Dermot PB; Fornace, Albert J; Borneman, James; Braun, Jonathan (BioMed Central, 2013)
      Background: Consistent compositional shifts in the gut microbiota are observed in IBD and other chronic intestinal disorders and may contribute to pathogenesis. The identities of microbial biomolecular mechanisms and ...
    • Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism 

      Tong, Maomeng; McHardy, Ian; Ruegger, Paul; Goudarzi, Maryam; Kashyap, Purna C; Haritunians, Talin; Li, Xiaoxiao; Graeber, Thomas G; Schwager, Emma; Huttenhower, Curtis; Fornace, Albert J; Sonnenburg, Justin L; McGovern, Dermot PB; Borneman, James; Braun, Jonathan (Nature Publishing Group, 2014)
      Fucosyltransferase 2 (FUT2) is an enzyme that is responsible for the synthesis of the H antigen in body fluids and on the intestinal mucosa. The H antigen is an oligosaccharide moiety that acts as both an attachment site ...