Browsing by Author "Dunn, Katherine L."

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    • P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation 

      Zheng, Hongwu; Ying, Haoqiang; Yan, Haiyan; Kimmelman, Alec C.; Hiller, David J.; Chen, An-Jou; Perry, Samuel R.; Tonon, Giovanni; Chu, Gerald C.; Ding, Zhihu; Stommel, Jayne M.; Dunn, Katherine L.; Wiedemeyer, Ruprecht; You, Mingjian J.; Brennan, Cameron; Wang, Y. Alan; Ligon, Keith L.; Wong, Wing H.; Chin, Lynda; DePinho, Ronald A. (2014)
      Glioblastoma (GBM) is a highly lethal brain tumor presenting as one of two subtypes with distinct clinical histories and molecular profiles. The primary GBM subtype presents acutely as high-grade disease that typically ...