Browsing by Author "Baron, David"
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Brown Adipose Tissue Blood Flow and Mass in Obesity: A Contrast Ultrasound Study in Mice
Clerte, Maëva; Baron, David William; Brouckaert, Peter; Ernande, Laura; Raher, Michael J.; Flynn, Aidan W.; Picard, Michael Howard; Bloch, Kenneth; Buys, Emmanuel; Scherrer-Crosbie, Marielle (Elsevier BV, 2013)Background: When activated by the sympathetic nervous system, brown adipose tissue (BAT) increases energy expenditure to produce heat. Augmenting BAT mass or increasing BAT activation could potentially be used to decrease ... -
Genetic modifiers of hypertension in soluble guanylate cyclase α1–deficient mice
Buys, Emmanuel; Raher, Michael J.; Kirby, Andrew; Mohd, Shahid; Baron, David William; Hayton, Sarah R.; Tainsh, Laurel T.; Sips, Patrick; Rauwerdink, Kristen M.; Yan, Qingshang; Tainsh, Robert E; Shakartzi, Hannah R.; Stevens, Christine; Decaluwé, Kelly; Rodrigues-Machado, Maria da Gloria; Malhotra, Rajeev; Van de Voorde, Johan; Wang, Tong; Brouckaert, Peter; Daly, Mark Joseph; Bloch, Kenneth Daniel (American Society for Clinical Investigation, 2012)Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1 subunit of soluble guanylate ... -
Halofuginone Prevents the Progression of Osteoarthritis
Khoynezhad, Shirin (2015-07-02)Background: Halofuginone (HF) is a natural product that has been shown to have therapeutic benefits in a variety of pathologic conditions, from cancer to autoimmune diseases. These beneficial effects are mainly through ...