Now showing items 1-5 of 5

    • Genetic risk variants associated with in situ breast cancer 

      Campa, Daniele; Barrdahl, Myrto; Gaudet, Mia M.; Black, Amanda; Chanock, Stephen J.; Diver, W. Ryan; Gapstur, Susan M.; Haiman, Christopher; Hankinson, Susan; Hazra, Aditi; Henderson, Brian; Hoover, Robert N.; Hunter, David J.; Joshi, Amit D.; Kraft, Peter; Le Marchand, Loic; Lindström, Sara; Willett, Walter; Travis, Ruth C.; Amiano, Pilar; Siddiq, Afshan; Trichopoulos, Dimitrios; Sund, Malin; Tjønneland, Anne; Weiderpass, Elisabete; Peeters, Petra H.; Panico, Salvatore; Dossus, Laure; Ziegler, Regina G.; Canzian, Federico; Kaaks, Rudolf (BioMed Central, 2015)
      Introduction: Breast cancer in situ (BCIS) diagnoses, a precursor lesion for invasive breast cancer, comprise about 20 % of all breast cancers (BC) in countries with screening programs. Family history of BC is considered ...
    • Genetic Variation in the Base Excision Repair Pathway, Environmental Risk Factors, and Colorectal Adenoma Risk 

      Corral, Roman; Lewinger, Juan Pablo; Joshi, Amit D.; Levine, A. Joan; Vandenberg, David J.; Haile, Robert W.; Stern, Mariana C. (Public Library of Science, 2013)
      Cigarette smoking, high alcohol intake, and low dietary folate levels are risk factors for colorectal adenomas. Oxidative damage caused by these three factors can be repaired through the base excision repair pathway (BER). ...
    • Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn’s Disease and Ulcerative Colitis 

      Khalili, Hamed; Malik, Sakshi; Ananthakrishnan, Ashwin N.; Garber, John J.; Higuchi, Leslie M.; Joshi, Amit; Peloquin, Joanna; Richter, James M.; Stewart, Kathleen O.; Curhan, Gary C.; Awasthi, Amit; Yajnik, Vijay; Chan, Andrew T. (Frontiers Media S.A., 2016)
      Background: Recent animal studies have identified that dietary salt intake may modify the risk and progression of autoimmune disorders through modulation of the IL-23/TH17 pathway, which is critical in the pathogenesis of ...
    • Joint Effects of Colorectal Cancer Susceptibility Loci, Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer 

      Hiraki, Linda T.; Joshi, Amit D.; Ng, Kimmie; Fuchs, Charles S.; Ma, Jing; Hazra, Aditi; Peters, Ulrike; Karlson, Elizabeth W.; Giovannucci, Edward; Kraft, Peter; Chan, Andrew T. (Public Library of Science, 2014)
      Background: Genome wide association studies (GWAS) have identified several SNPs associated with colorectal cancer (CRC) susceptibility. Vitamin D is also inversely associated with CRC risk. Methods: We examined main and ...
    • Tobacco smoking, polymorphisms in carcinogen metabolism enzyme genes, and risk of localized and advanced prostate cancer: results from the California Collaborative Prostate Cancer Study 

      Shahabi, Ahva; Corral, Román; Catsburg, Chelsea; Joshi, Amit D; Kim, Andre; Lewinger, Juan Pablo; Koo, Jocelyn; John, Esther M; Ingles, Sue A; Stern, Mariana C (Blackwell Publishing Ltd, 2014)
      The relationship between tobacco smoking and prostate cancer (PCa) remains inconclusive. This study examined the association between tobacco smoking and PCa risk taking into account polymorphisms in carcinogen metabolism ...