Browsing by Author "Harris, Holly R."

Now showing items 1-6 of 6

    • Alcohol Intake and Mortality among Women with Invasive Breast Cancer 

      Harris, Holly Ruth; Bergkvist, L; Wolk, A (Nature Publishing Group, 2012)
      Background: Alcohol intake has consistently been associated with increased breast cancer incidence in epidemiological studies. However, the relation between alcohol and survival after breast cancer diagnosis is less clear. ...

    • Folate, vitamin B6, vitamin B12, methionine and alcohol intake in relation to ovarian cancer risk 

      Harris, Holly Ruth; Cramer, Daniel William; Vitonis, Allison F.; DePari, Mary; Terry, Kathryn Lynne (Wiley-Blackwell, 2011)
      Folate, methionine, vitamin B6, and vitamin B12 may influence carcinogenesis due to their roles in the one-carbon metabolism pathway which is critical for DNA synthesis, methylation, and repair. Low intake of these nutrients ...

    • Genetic variation in telomere maintenance genes in relation to ovarian cancer survival 

      Harris, Holly Ruth; De Vivo, Immaculata; Titus, Linda J.; Vitonis, Allison F.; Wong, Jason; Cramer, Daniel William; Terry, Kathryn Lynne (e-Century Publishing, 2012)
      Telomeres are repetitive non-coding DNA sequences at the ends of chromosomes that provide protection against chromosomal instability. Telomere length and stability are influenced by proteins, including telomerase which is ...

    • Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci 

      Rahmioglu, Nilufer; Macgregor, Stuart; Drong, Alexander W.; Hedman, Åsa K.; Harris, Holly R.; Randall, Joshua C.; Prokopenko, Inga; Nyholt, Dale R.; Morris, Andrew P.; Montgomery, Grant W.; Missmer, Stacey A.; Lindgren, Cecilia M.; Zondervan, Krina T. (2015)
      Endometriosis is a chronic inflammatory condition in women that results in pelvic pain and subfertility, and has been associated with decreased body mass index (BMI). Genetic variants contributing to the heritable component ...

    • Leukocyte DNA as Surrogate for the Evaluation of Imprinted Loci Methylation in Mammary Tissue DNA 

      Barault, Ludovic; Ellsworth, Rachel E.; Harris, Holly Ruth; Valente, Allyson L.; Shriver, Craig D.; Michels, Karin B. (Public Library of Science, 2013)
      There is growing interest in identifying surrogate tissues to identify epimutations in cancer patients since primary target tissues are often difficult to obtain. Methylation patterns at imprinted loci are established ...

    • Parental smoking during pregnancy and risk of overweight and obesity in the daughter 

      Harris, Holly R.; Willett, Walter C.; Michels, Karin B. (2013)
      Objective: Emerging evidence suggests that prenatal exposures may affect long-term health outcomes. In utero exposure to smoking is associated with an increased risk of overweight and obesity in children and adolescents. ...