Now showing items 1-5 of 5

    • Acute seizure suppression by transcranial direct current stimulation in rats 

      Dhamne, Sameer C; Ekstein, Dana; Zhuo, Zhihong; Gersner, Roman; Zurakowski, David; Loddenkemper, Tobias; Pascual-Leone, Alvaro; Jensen, Frances E; Rotenberg, Alexander (John Wiley & Sons, Ltd, 2015)
      Objective: Cathodal transcranial direct current stimulation (tDCS) is a focal neuromodulation technique that suppresses cortical excitability by low-amplitude constant electrical current, and may have an antiepileptic ...
    • Chronopharmacology of Anti-Convulsive Therapy 

      Ramgopal, Sriram; Thome-Souza, Sigride; Loddenkemper, Tobias (Current Science Inc., 2013)
      Approximately one-third of patients with epilepsy continue to have seizures despite antiepileptic therapy. Many seizures occur in diurnal, sleep/wake, circadian, or even monthly patterns. The relationship between biomarkers ...
    • Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management 

      Sánchez Fernández, Iván; Chapman, Kevin E.; Peters, Jurriaan M.; Harini, Chellamani; Rotenberg, Alexander; Loddenkemper, Tobias (Hindawi Publishing Corporation, 2013)
      Continuous spikes and waves during sleep (CSWS) is an epileptic encephalopathy characterized in most patients by (1) difficult to control seizures, (2) interictal epileptiform activity that becomes prominent during sleep ...
    • Risk Factors Associated with Death in In-Hospital Pediatric Convulsive Status Epilepticus 

      Loddenkemper, Tobias; Syed, Tanvir U.; Ramgopal, Sriram; Gulati, Deepak; Thanaviratananich, Sikawat; Kothare, Sanjeev Vithal; Alshekhlee, Amer; Koubeissi, Mohamad Z. (Public Library of Science, 2012)
      Objective: To evaluate in-patient mortality and predictors of death associated with convulsive status epilepticus (SE) in a large, multi-center, pediatric cohort. Patients and Methods: We identified our cohort from the KID ...
    • Subunit Composition of Neurotransmitter Receptors in the Immature and in the Epileptic Brain 

      Sánchez Fernández, Iván; Loddenkemper, Tobias (Hindawi Publishing Corporation, 2014)
      Neuronal activity is critical for synaptogenesis and the development of neuronal networks. In the immature brain excitation predominates over inhibition facilitating the development of normal brain circuits, but also ...