Now showing items 1-3 of 3

    • Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins 

      Liang, Xinwen; Kaya, Alaattin; Zhang, Yan; Le, Dung T; Hua, Deame; Gladyshev, Vadim N (BioMed Central, 2012)
      Background: Methionine (Met) residues in proteins can be readily oxidized by reactive oxygen species to Met sulfoxide (MetO). MetO is a promising physiological marker of oxidative stress and its inefficient repair by MetO ...
    • Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes 

      Mariotti, Marco; Ridge, Perry G.; Zhang, Yan; Lobanov, Alexei; Pringle, Thomas H.; Guigo, Roderic; Hatfield, Dolph L.; Gladyshev, Vadim (Public Library of Science, 2012)
      Background: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24. ...
    • Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells 

      Rice, William; Zhang, Yan; Chen, Ying; Matsuzaki, Toshiyuki; Brown, Dennis; Lu, Hua A Jenny (Public Library of Science, 2012)
      The kidney maintains water homeostasis by modulating aquaporin 2 (AQP2) on the plasma membrane of collecting duct principal cells in response to vasopressin (VP). VP mediated phosphorylation of AQP2 at serine 256 is critical ...