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    • PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice 

      Saito, Kenji; He, Yanlin; Yang, Yongjie; Zhu, Liangru; Wang, Chunmei; Xu, Pingwen; Hinton, Antentor Othrell; Yan, Xiaofeng; Zhao, Jean; Fukuda, Makoto; Tong, Qingchun; Clegg, Deborah J.; Xu, Yong (Nature Publishing Group, 2016)
      Estrogens act in the ventromedial hypothalamic nucleus (VMH) to regulate body weight homeostasis. However, the molecular mechanisms underlying these estrogenic effects are unknown. We show that activation of estrogen ...