Now showing items 1-8 of 8

    • Comparative Effectiveness Research Using Observational Data: Active Comparators to Emulate Target Trials with Inactive Comparators 

      Huitfeldt, Anders; Hernan, Miguel A.; Kalager, Mette; Robins, James M. (AcademyHealth, 2016)
      Introduction: Because a comparison of noninitiators and initiators of treatment may be hopelessly confounded, guidelines for the conduct of observational research often recommend using an “active” comparator group consisting ...
    • Efavirenz versus boosted atazanavir-containing regimens and immunologic, virologic, and clinical outcomes: A prospective study of HIV-positive individuals 

      Cain, Lauren E.; Caniglia, Ellen C.; Phillips, Andrew; Olson, Ashley; Muga, Roberto; Pérez-Hoyos, Santiago; Abgrall, Sophie; Costagliola, Dominique; Rubio, Rafael; Jarrín, Inma; Bucher, Heiner; Fehr, Jan; van Sighem, Ard; Reiss, Peter; Dabis, François; Vandenhende, Marie-Anne; Logan, Roger; Robins, James; Sterne, Jonathan A. C.; Justice, Amy; Tate, Janet; Touloumi, Giota; Paparizos, Vasilis; Esteve, Anna; Casabona, Jordi; Seng, Rémonie; Meyer, Laurence; Jose, Sophie; Sabin, Caroline; Hernán, Miguel A. (Wolters Kluwer Health, 2016)
      Abstract Objective: To compare regimens consisting of either ritonavir-boosted atazanavir or efavirenz and a nucleoside reverse transcriptase inhibitor (NRTI) backbone with respect to clinical, immunologic, and virologic ...
    • Identifiability, Exchangeability and Confounding revisited 

      Greenland, Sander; Robins, James Matthew (BioMed Central, 2009)
      In 1986 the International Journal of Epidemiology published "Identifiability, Exchangeability and Epidemiological Confounding". We review the article from the perspective of a quarter century after it was first drafted and ...
    • Oseltamivir for treatment and prevention of pandemic influenza A/H1N1 virus infection in households, Milwaukee, 2009 

      Cowling, Benjamin J; Fang, Vicky J; Hagy, Angela; Reshef, David; Biedrzycki, Paul; Goldstein, Edward; O'Hagan, Justin John; Danon, Leon; Miller, Joel C.; Robins, James Matthew; Lipsitch, Marc (BioMed Central, 2010)
      Background: During an influenza pandemic, a substantial proportion of transmission is thought to occur in households. We used data on influenza progression in individuals and their contacts collected by the City of Milwaukee ...
    • Pandemic Influenza: Risk of Multiple Introductions and the Need to Prepare for Them 

      Mills, Christina E; Robins, James M.; Bergstrom, Carl T; Lipsitch, Marc (Public Library of Science (PLoS), 2006)
    • Semi-Parametric Methods for Missing Data and Causal Inference 

      Sun, BaoLuo (2016-05-14)
      In this dissertation, we propose methodology to account for missing data as well as a strategy to account for outcome heterogeneity. Missing data occurs frequently in empirical studies in health and social sciences, often ...
    • Using Observational Data to Calibrate Simulation Models 

      Murray, Eleanor Jane; Robins, James M.; Seage, George R.; Lodi, Sara; Hyle, Emily Parker; Reddy, Krishna Podditur; Freedberg, Kenneth Alan; Hernan, Miguel Angel (SAGE Publications, 2017)
      BACKGROUND: Individual-level simulation models are valuable tools for comparing the impact of clinical or public health interventions on population health and cost outcomes over time. However, a key challenge is ensuring ...
    • When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries: A Prospective Observational Study 

      Caniglia, Ellen C.; Sabin, Caroline; Robins, James M.; Logan, Roger; Cain, Lauren E.; Abgrall, Sophie; Mugavero, Michael J.; Hernandez-Diaz, Sonia; Meyer, Laurence; Seng, Remonie; Drozd, Daniel R.; Seage, George R.; Bonnet, Fabrice; Dabis, Francois; Moore, Richard R.; Reiss, Peter; van Sighem, Ard; Mathews, William C.; del Amo, Julia; Moreno, Santiago; Deeks, Steven G.; Muga, Roberto; Boswell, Stephen L.; Ferrer, Elena; Eron, Joseph J.; Napravnik, Sonia; Jose, Sophie; Phillips, Andrew; Olson, Ashley; Justice, Amy C.; Tate, Janet P.; Bucher, Heiner C.; Egger, Matthias; Touloumi, Giota; Sterne, Jonathan A.; Costagliola, Dominique; Saag, Michael; Hernán, Miguel A. (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2016)
      Objective: To illustrate an approach to compare CD4 cell count and HIV-RNA monitoring strategies in HIV-positive individuals on antiretroviral therapy (ART). Design: Prospective studies of HIV-positive individuals in Europe ...