Browsing by Author "Sliz, Piotr"

Now showing items 1-7 of 7

    • Adapting Federated Cyberinfrastructure for Shared Data Collection Facilities in Structural Biology 

      Stokes-Rees, Ian; Levesque, Ian; Murphy, Frank V.; Yang, Wei; Deacon, Ashley; Sliz, Piotr (International Union of Crystallography, 2012)
      Early stage experimental data in structural biology is generally unmaintained and inaccessible to the public. It is increasingly believed that this data, which forms the basis for each macromolecular structure discovered ...

    • Collaboration gets the most out of software 

      Morin, Andrew; Eisenbraun, Ben; Key, Jason; Sanschagrin, Paul C; Timony, Michael A; Ottaviano, Michelle; Sliz, Piotr (eLife Sciences Publications, Ltd, 2013)
      By centralizing many of the tasks associated with the upkeep of scientific software, SBGrid allows researchers to spend more of their time on research.

    • A Grid-Enabled Web Service for Low-Resolution Crystal Structure Refinement 

      O’Donovan, Daniel J.; Stokes-Rees, Ian; Nam, Yunsun; Blacklow, Stephen C.; Schröder, Gunnar F.; Brunger, Axel T.; Sliz, Piotr (International Union of Crystallography, 2012)
      Deformable elastic network (DEN) restraints have proved to be a powerful tool for refining structures from low-resolution X-ray crystallographic data sets. Unfortunately, optimal refinement using DEN restraints requires ...

    • Lipid-Protein Interactions in Double-Layered Two-Dimensional AQP0 Crystals 

      Gonen, Tamir; Cheng, Yifan; Sliz, Piotr; Hiroaki, Yoko; Fujiyoshi, Yoshinori; Harrison, Stephen; Walz, Thomas (Nature Publishing Group, 2005)
      Lens-specific aquaporin-0 (AQP0) functions as a specific water pore and forms the thin junctions between fibre cells. We describe a 1.9 Å resolution structure of junctional AQP0, determined by electron crystallography of ...

    • Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides 

      Lelyveld, Victor S.; Björkbom, Anders; Ransey, Elizabeth M.; Sliz, Piotr; Szostak, Jack W. (American Chemical Society, 2015)
      High affinity RNA-protein interactions are critical to cellular function, but directly identifying the determinants of binding within these complexes is often difficult. Here, we introduce a stable isotope mass labeling ...

    • A Quick Guide to Software Licensing for the Scientist-Programmer 

      Morin, Andrew; Urban, Jennifer; Sliz, Piotr (Public Library of Science, 2012)

    • Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4) 

      Thornton, James E.; Du, Peng; Jing, Lili; Sjekloca, Ljiljana; Lin, Shuibin; Grossi, Elena; Sliz, Piotr; Zon, Leonard I.; Gregory, Richard I. (Oxford University Press, 2014)
      Recent small RNA sequencing data has uncovered 3′ end modification of mature microRNAs (miRNAs). This non-templated nucleotide addition can impact miRNA gene regulatory networks through the control of miRNA stability or ...