Now showing items 1-5 of 5

    • 5-Hydroxymethylcytosine Expression in Metastatic Melanoma versus Nodal Nevus in Sentine Lymph Node Biopsies 

      Lee, Jonathan J.; Granter, Scott R.; Laga, Alvaro C.; Saavedra, Arturo; Zhan, Qian; Guo, Weimin; Xu, Shuyun; Murphy, George F.; Lian, Christine G. (2014)
      Sentinel lymph node biopsies are conducted to stage patients with newly-diagnosed melanomas that have histopathologic attributes conferring defined levels of metastatic potential. Because benign nevic cells may also form ...
    • Analysis of a Mouse Skin Model of Tuberous Sclerosis Complex 

      Guo, Yanan; Dreier, John R.; Cao, Juxiang; Du, Heng; Granter, Scott R.; Kwiatkowski, David J. (Public Library of Science, 2016)
      Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor suppressor gene syndrome in which patients develop several types of tumors, including facial angiofibroma, subungual fibroma, Shagreen patch, angiomyolipomas, ...
    • DHODH modulates transcriptional elongation in the neural crest and melanoma 

      White, Richard Mark; Cech, Jennifer; Ratanasirintrawoot, Sutheera; Lin, Charles P.; Rahl, Peter B.; Burke, Christopher J.; Langdon, Erin; Tomlinson, Matthew L.; Mosher, Jack; Kaufman, Charles Kore; Chen, Frank; Long, Hannah K.; Kramer, Martin; Datta, Sumon Michael; Neuberg, Donna S.; Granter, Scott R.; Young, Richard A.; Morrison, Sean; Wheeler, Grant N.; Zon, Leonard Ira (Nature Publishing Group, 2011)
    • Integrative Genome Comparison of Primary and Metastatic Melanomas 

      Kabbarah, Omar; Nogueira, Cristina; Feng, Bin; Bosenberg, Marcus; Scott, Kenneth L.; Xiao, Yonghong; Cordon-Cardo, Carlos; Wagner, Stephan N.; Brennan, Cameron; Nazarian, Rosalynn; Wu, Min; Kwong, Lawrence Noc-Woon; Granter, Scott R.; Ramaswamy, Sridhar; Golub, Todd R.; Duncan, Lyn M.; Chin, Lynda (Public Library of Science, 2010)
      A cardinal feature of malignant melanoma is its metastatic propensity. An incomplete view of the genetic events driving metastatic progression has been a major barrier to rational development of effective therapeutics and ...
    • Tetraspanin CD151 plays a key role in skin squamous cell carcinoma 

      Li, Qinglin; Yang, Xiuwei H.; Xu, Fenghui; Sharma, Chandan; Wang, Hong-Xing; Knoblich, Konstantin; Rabinovitz, Isaac; Granter, Scott R.; Hemler, Martin E. (2012)
      Here we provide the first evidence that tetraspanin CD151 can support de novo carcinogenesis. During two-stage mouse skin chemical carcinogenesis, CD151 reduces tumor lag time and increases incidence, multiplicity, size, ...