Browsing by Author "Marshall, Jamie"
Now showing items 1-2 of 2
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Efficient, Continuous Mutagenesis in Human Cells Using a Pseudo-Random DNA Editor
Chen, Haiqi; Liu, Sophia; Padula, Samuel; Lesman, Daniel; Griswold, Kettner; Lin, Allen; Zhao, Tongtong; Marshall, Jamie; Chen, Fei (Springer Science and Business Media LLC, 2019-12-16)Here, we describe TRACE, a method that enables continuous, targeted mutagenesis in human cells using a cytidine deaminase fused to T7 RNA polymerase. TRACE induces high rates of mutagenesis over multiple cell generations ... -
Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2
Stickels, Robert; Murray, Evan; Kumar, Pawan; Li, Jilong; Marshall, Jamie; Di Bella, Daniela; Arlotta, Paola; Macosko, Evan; Chen, Fei (Springer Science and Business Media LLC, 2020-12-07)