Browsing by Author "Oaklander, Anne"
Now showing items 1-20 of 33
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7T MRI of spinal cord injury
Cohen-Adad, J.; Zhao, Wei Chen; Wald, Lawrence Leroy; Oaklander, Anne Louise (Ovid Technologies (Wolters Kluwer Health), 2012)A man with 25 years of mild left neck, arm, and leg paresthesias had initial MRI in 1996 identifying a left C3-4 dorsal horn cavernous hemangioma. In 1997, hemorrhage (C3-7) and resection induced left arm > leg proprioceptive ... -
Advances in the Understanding of the Pathogenesis and Epidemiology of Herpes Zoster
Gershon, Anne A.; Gershon, Michael D.; Breuer, Judith; Levin, Myron J.; Oaklander, Anne; Griffiths, Paul D. (Elsevier BV, 2010-05)The primary varicella zoster virus (VZV) infection results in chickenpox (varicella), which is transmitted via the airborne route. VZV is highly infectious, but in the USA the incidence of varicella has been reduced by ... -
Bilateral Somatosensory Cortex Disinhibition in Complex Regional Pain Syndrome Type I
Oaklander, Anne Louise; Lenz, M.; Krumova, E.; Hoeffken, O.; Stude, P.; Lissek, S.; Schwenkreis, P.; Reinersmann, A.; Frettloeh, J.; Richter, H.; Tegenthoff, M.; Maier, C. (Ovid Technologies (Wolters Kluwer Health), 2012) -
Case 16-2004
Amato, Anthony A.; Oaklander, Anne Louise (New England Journal of Medicine (NEJM/MMS), 2004) -
Cervical spinal cord injection of epidural corticosteroids: Comprehensive longitudinal study including multiparametric magnetic resonance imaging
Cohen-Adad, Julien; Buchbinder, Bradley R.; Oaklander, Anne Louise (Ovid Technologies (Wolters Kluwer Health), 2012)Despite widespread use, the efficacy of epidural corticosteroid injections (ESI) for osteoarthritis-associated neck or radicular pain remains uncertain, so even rare serious complications enter into discussions about use. ... -
Cold Blockade of Axonal Transport Activates Premitotic Activity of Schwann Cells and Wallerian Degeneration
Oaklander, Anne Louise; Spencer, Peter S. (Wiley, 1988)Between 3 and 4 days after transection of cat sciatic nerve, Schwann cell-associated premitotic activity spreads anterogradely along degenerating distal nerve stumps at a rate of approximately 200 mm/day. We inves- tigated ... -
Common Neuropathic Itch Syndromes
Oaklander, Anne Louise (Acta Dermato-Venereologica, 2012)Patients with chronic itch are diagnosed and treated by dermatologists. However, itch is a neural sensation and some forms of chronic itch are the presenting symptoms of neurological diseases. Dermatologists need some ... -
Comparing Partial and Total Tibial-Nerve Axotomy: Long-Term Effects on Prevalence and Location of Evoked Pain Behaviors
Unal-Cevik, Isin; Oaklander, Anne Louise (Wiley, 2010)Monophasic (one-time) nerve injuries heal without clinically significant residua in most cases, but rare individuals are left with neuropathic pain, even after seem- ingly minor lesions. The effects of lesion size on risk ... -
Corneal innervation as a window to peripheral neuropathies
Ferrari, Giulio; Nallasamy, Nambi; Downs, Heather; Dana, Reza; Oaklander, Anne Louise (Elsevier BV, 2013)The cornea receives the densest sensory innervation of the body, which is exclusively from small-fiber nociceptive (pain-sensing) neurons. These are similar to those in the skin of the legs, the standard location for ... -
Dermatomal Scratching After Intramedullary Quisqualate Injection: Correlation With Cutaneous Denervation
Brewer, Kori L.; Lee, Jeungchan; Downs, Heather; Oaklander, Anne Louise; Yezierski, Robert P. (Elsevier BV, 2008)Central nervous system lesions cause peripheral dysfunctions currently attributed to central cell death that compromises function of intact peripheral nerves. Injecting quisqualate (QUIS) into the rat spinal cord models ... -
Effects of distal nerve injuries on dorsal-horn neurons and glia: Relationships between lesion size and mechanical hyperalgesia
Lee, Jace; Siegel, Sandra Marie; Oaklander, Anne Louise (Elsevier BV, 2009)Penetrating limb injuries are common and usually heal without long-lasting effects, even when nerves are cut. However, rare nerve-injury patients develop prolonged and disabling chronic pain (neuralgia). When pain severity ... -
Endoneurial pathology of the needlestick-nerve-injury model of Complex Regional Pain Syndrome, including rats with and without pain behaviors
Klein, M.M.; Lee, Jeung Woon; Siegel, Sandra Marie; Downs, H.M.; Oaklander, Anne Louise (Wiley-Blackwell, 2012)Current rodent models of neuropathic pain produce pain hypersensitivity in almost all lesioned animals and not all identified experimental effects are pain specific. 18G needlestick-nerve-injury (NNI) to one tibial nerve ... -
Evidence of small-fiber neuropathy (SFN) in two patients with unexplained genital sensory loss and sensory urinary cystopathy
AbdelRazek, Mahmoud A.; Chwalisz, Bart K; Oaklander, Anne Louise; Venna, Nagagopal (Elsevier BV, 2017)The term small-fiber neuropathy (SFN) refers to the type of polyneuropathies that preferentially damage the small unmyelinated and thinly myelinated sensory or autonomic neurons [1]. Skin biopsy to determine the epidermal ... -
Experimental Comparison of Parametric Versus Nonparametric Analyses of Data From the Cold Pressor Test
Treister, Roi; Nielsen, Christopher; Stubhaug, Audun; Farrar, John T.; Pud, Dorit; Sawilowsky, Shlomo; Oaklander, Anne Louise (Elsevier BV, 2015)Parametric statistical methods are common in human pain research. They require normally distributed data, but this assumption is rarely tested. The current study analyzes the appropriateness of parametric testing for ... -
Initial Development and Validation of a Patient-Reported Symptom Survey for Small-Fiber Polyneuropathy
Treister, Roi; Lodahl, Mette; Lang, Magdalena; Tworoger, Shelley Slate; Sawilowsky, Shlomo; Oaklander, Anne Louise (Elsevier BV, 2017)Small-fiber polyneuropathy (SFPN) affects unmyelinated and thinly myelinated peripheral axons. Several questionnaires have been developed to assess polyneuropathy from diabetes or chemotherapy, but none for SFPN from other ... -
IVIg for apparently autoimmune small-fiber polyneuropathy: first analysis of efficacy and safety
Liu, Xiaolei; Treister, Roi; Lang, Magdalena; Oaklander, Anne Louise (SAGE Publications, 2018)Objectives: Small-fiber polyneuropathy (SFPN) has various underlying causes, including associations with systemic autoimmune conditions. We have proposed a new cause; small-fiber-targeting autoimmune diseases akin to ... -
Needlestick Distal Nerve Injury in Rats Models Symptoms of Complex Regional Pain Syndrome
Siegel, Sandra Marie; Lee, Jeungchan; Oaklander, Anne Louise (Ovid Technologies (Wolters Kluwer Health), 2007)BACKGROUND: Complex Regional Pain Syndrome (CRPS)-I consists of chronic limb pain and dysautonomia triggered by traumas that sometime seem too trivial to be causative. Several pathological studies have identified minor ... -
Neuropathic Itch
Oaklander, Anne Louise (Frontline Medical Communications, Inc., 2011)Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still unknown. All neurological disease categories ... -
Non-invasive Transcranial Magnetic Stimulation (TMS) of the Motor Cortex for Neuropathic Pain—At the Tipping Point?
Treister, Roi; Lang, Magdalena; Klein, Max M.; Oaklander, Anne Louise (Rambam Health Care Campus, 2013)The term “neuropathic pain” (NP) refers to chronic pain caused by illnesses or injuries that damage peripheral or central pain-sensing neural pathways to cause them to fire inappropriately and signal pain without cause. ... -
Nucleotide Signaling and Cutaneous Mechanisms of Pain Transduction
Dussor, G.; Koerber, H.R.; Oaklander, Anne; Rice, F.L.; Molliver, D.C. (Elsevier BV, 2009-04)Sensory neurons that innervate the skin provide critical information about physical contact between the organism and the environment, including information about potentially-damaging stimuli that give rise to the sensation ...