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    • Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma 

      Igartua, Catherine; Myers, Rachel A.; Mathias, Rasika A.; Pino-Yanes, Maria; Eng, Celeste; Graves, Penelope E.; Levin, Albert M.; Del-Rio-Navarro, Blanca E.; Jackson, Daniel J.; Livne, Oren E.; Rafaels, Nicholas; Edlund, Christopher K.; Yang, James J.; Huntsman, Scott; Salam, Muhammad T.; Romieu, Isabelle; Mourad, Raphael; Gern, James E.; Lemanske, Robert F.; Wyss, Annah; Hoppin, Jane A.; Barnes, Kathleen C.; Burchard, Esteban G.; Gauderman, W. James; Martinez, Fernando D.; Raby, Benjamin A.; Weiss, Scott T.; Williams, L. Keoki; London, Stephanie J.; Gilliland, Frank D.; Nicolae, Dan L.; Ober, Carole (Nature Pub. Group, 2015)
      Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (<1%) and low-frequency (1–5%) variants using the Illumina HumanExome ...