Browsing by Author "Komaroff, Anthony"

Now showing items 1-20 of 33

    • Acute Dysuria in Women 

      Komaroff, Anthony (Massachusetts Medical Society, 1984-02-09)
      AS many as a quarter of adult women may experience an episode of acute dysuria each year.1 Dysuria is one of the most common clinical problems seen by clinicians in the developed Western nations,2 3 4 accounting for over ...

    • Acute Phase Responses and Cytokine Secretion in Chronic Fatigue Syndrome 

      Cannon, Joseph G.; Angel, Jonathan B.; Ball, Richard W.; Abad, Leslie W.; Fagioli, Laura; Komaroff, Anthony (Springer Science and Business Media LLC, 1999-11)
      This study addresses the hypothesis that clinical manifestations of chronic fatigue syndrome (CFS) are due in part to abnormal production of or sensitivity to cytokines such as interleukin-1beta (IL-1beta) and IL-6 under ...

    • Alternatives to Metronidazole 

      Komaroff, Anthony; Cohen, Alan B.; McCue, Jack D. (American Medical Association (AMA), 1976-05-10)
      To the Editor.— The recent warning in The Medical Letter1 regarding the mutagenicity and possible carcinogenicity of metronidazole (Flagyl) raises the question of whether there is an alternative treatment of equal efficacy ...

    • Association Between Cigarette Smoking and Acute Respiratory Tract Illness in Young Adults 

      Aronson, Mark; Weiss, Scott; Ben, Ricca L.; Komaroff, Anthony (American Medical Association (AMA), 1982-07-09)
      The association of cigarette smoking with the occurrence and severity of an acute respiratory tract illness (ARTI) was studied. Clinical data were obtained prospectively on 867 men and women with an ARTI and on a control ...

    • Clinical Laboratory Test Findings in Patients with Chronic Fatigue Syndrome 

      Bates, David; Buchwald, Dedra; Lee, Joshua; Kith, Phalla; Doolittle, Teresa; Rutherford, Cynthia; Churchill, W.; Schur, Peter; Wener, Mark; Wybenga, Donald; Winkelman, James; Komaroff, Anthony (American Medical Association (AMA), 1995-01-09)
      Background: Results of readily available clinical laboratory tests in patients with chronic fatigue syndrome were compared with results in healthy control subjects. Methods: Cases consisted of all 579 patients who met ...

    • A Comparison of Pregnancies That Occur Before and After the Onset of Chronic Fatigue Syndrome 

      Schacterle, Richard; Komaroff, Anthony L. (American Medical Association (AMA), 2004)
      Background Many women with chronic fatigue syndrome (CFS) fear that pregnancy will worsen their condition, increase the risks of maternal complications of pregnancy, or threaten the health of their offspring. Little ...

    • Cost and Quality in the Use of Blood Bank Services for Normal Deliveries, Cesarean Sections, and Hysterectomies 

      Palmer, R. Heather; Kane, J. Gregory; Churchill, W.; Goldman, Lee; Komaroff, Anthony (American Medical Association (AMA), 1986-07-11)
      To reduce costs, preserve blood supplies, and enhance the safety of blood use during emergencies, the Department of Obstetrics and Gynecology and the blood bank at a teaching hospital recommended replacing pre-delivery ...

    • Cost Effectiveness of Lead Screening 

      Berwick, Donald; Komaroff, Anthony (Massachusetts Medical Society, 1982-06-10)
      Lead-screening programs may reduce childhood disabilities, but at what cost? Through a review of the literature, we performed a cost-effectiveness analysis in which the costs, savings, and health benefits of two lead-screening ...

    • Distinct plasma immune signatures in ME/CFS are present early in the course of illness 

      Hornig, M.; Montoya, J. G.; Klimas, N. G.; Levine, S.; Felsenstein, Donna; Bateman, L.; Peterson, D. L.; Gottschalk, C. G.; Schultz, A. F.; Che, X.; Eddy, M. L.; Komaroff, Anthony L.; Lipkin, W. I. (American Association for the Advancement of Science (AAAS), 2015)
      Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an unexplained incapacitating illness that may affect up to 4 million people in the United States alone. There are no validated laboratory tests for diagnosis ...

    • Does the Computerized Display of Charges Affect Inpatient Ancillary Test Utilization? 

      Bates, David; Kuperman, Gilad J.; Jha, Ashish; Teich, Jonathan; Orav, Endel; Ma'luf, Nell; Onderdonk, Andrew; Pugatch, Robert; Wybenga, Donald; Winkelman, James; Brennan, Troyen; Komaroff, Anthony; Tanasijevic, Milenko (American Medical Association (AMA), 1997-11-24)
      Background: The computerized display of charges for ancillary tests in outpatients has been found to affect physician-ordering behavior, but this issue has not been studied in inpatients. Objective: To assess whether ...

    • The Dysuria-Pyuria Syndrome 

      Komaroff, Anthony; Friedland, Gerald (Massachusetts Medical Society, 1980-08-21)

    • EEG spectral coherence data distinguish chronic fatigue syndrome patients from healthy controls and depressed patients-A case control study 

      Duffy, Frank Hopkins; McAnulty, Gloria; McCreary, Michelle C; Cuchural, George J; Komaroff, Anthony L. (Springer Nature, 2011)
      Background: Previous studies suggest central nervous system involvement in chronic fatigue syndrome (CFS), yet there are no established diagnostic criteria. CFS may be difficult to differentiate from clinical depression. ...

    • Efficiency and Cost of Primary Care by Nurses and Physician Assistants 

      Greenfield, Sheldon; Komaroff, Anthony; Pass, Theodore M.; Anderson, Hjalmar; Nessim, Sharon (Massachusetts Medical Society, 1978-02-09)
      We conducted a prospective study in a prepaid primary-care practice (health-maintenance organization) of a system in which nurses and physician assistants used protocols, and compared the efficiency and costs of this ...

    • Failure to Confirm XMRV/MLVs in the Blood of Patients with Chronic Fatigue Syndrome: A Multi-Laboratory Study 

      Simmons, G.; Glynn, S. A.; Komaroff, Anthony L.; Mikovits, J. A.; Tobler, L. H.; Hackett, J.; Tang, N.; Switzer, W. M.; Heneine, W.; Hewlett, I. K.; Zhao, J.; Lo, S.-C.; Alter, H. J.; Linnen, J. M.; Gao, K.; Coffin, J. M.; Kearney, M. F.; Ruscetti, F. W.; Pfost, M. A.; Bethel, J.; Kleinman, S.; Holmberg, J. A.; Busch, M. P. (American Association for the Advancement of Science (AAAS), 2011)
      Murine leukemia viruses (MLV), including xenotropic-MLV-related virus (XMRV), have been controversially linked to chronic fatigue syndrome (CFS). To explore this issue in greater depth, we compiled coded replicate samples ...

    • Frequency of 'Chronic Active Epstein-Barr Virus Infection' in a General Medical Practice 

      Sullivan, John; Komaroff, Anthony; Buchwald, Dedra (American Medical Association (AMA), 1987-05-01)
      Twenty-one percent of 500 unselected patients, aged 17 to 50 years, seeking primary care for any reason were found to be suffering from a chronic fatigue syndrome consistent with "chronic active Epstein-Barr virus (EBV) ...

    • Gene Editing Using CRISPR 

      Komaroff, Anthony L. (American Medical Association (AMA), 2017)
      The gene-editing technique known as CRISPR (clustered regularly interspaced short palindromic repeats) is only 5 years old, yet it has galvanized biomedical research and raised important ethical questions. What is it, how ...

    • Guided Medication Dosing for Inpatients with Renal Insufficiency 

      Chertow, Glenn M.; Lee, Joshua; Kuperman, Gilad J.; Burdick, Elisabeth; Horsky, Jan; Seger, Diane L.; Lee, Rita; Mekala, Aparna; Song, Jean; Komaroff, Anthony; Bates, David (American Medical Association (AMA), 2001-12-12)
      Context: Usual drug-prescribing practices may not consider the effects of renal insufficiency on the disposition of certain drugs. Decision aids may help optimize prescribing behavior and reduce medical error. Objective: ...

    • Human Herpesvirus 7 is a T-Lymphotropic Virus and is Related to, but Significantly Different from, Human Herpesvirus 6 and Human Cytomegalovirus 

      Berneman, Zwi N.; Ablashi, Dharam; Li, Ge; Eger-Fletcher, Maureen; Reitz, Marvin S.; Hung, Chia-Ling; Brus, Irena; Komaroff, Anthony; Gallo, Robert C. (National Academy of Sciences, 1992-11-01)
      An independent strain (JI) of human herpesvirus 7 (HHV-7) was isolated from a patient with chronic fatigue syndrome (CFS). No significant association could be established by seroepidemiology between HHV-7 and CFS. HHV-7 ...

    • Inflammation correlates with symptoms in chronic fatigue syndrome 

      Komaroff, Anthony L. (Proceedings of the National Academy of Sciences, 2017)
      It is not unusual for patients who say they are sick to have normal results on standard laboratory testing. The physician often concludes that there is no “real” illness and that the patients’ symptoms likely stem from a ...

    • The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro 

      Arbuckle, J. H.; Medveczky, M. M.; Luka, J.; Hadley, S. H.; Luegmayr, A.; Ablashi, D.; Lund, T. C.; Tolar, J.; De Meirleir, K.; Montoya, J. G.; Komaroff, Anthony L.; Ambros, P. F.; Medveczky, P. G. (Proceedings of the National Academy of Sciences, 2010)
      Previous research has suggested that human herpesvirus-6 (HHV-6) may integrate into host cell chromosomes and be vertically transmitted in the germ line, but the evidence—primarily fluorescence in situ hybridization (FISH)—is ...