Browsing by Author "Welling, Duane"
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Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma
Plotkin, Scott Randall; Halpin, Chris; Blakeley, Jaishri O.; Slattery, William H.; Welling, Duane Bradley; Chang, Susan M.; Loeffler, Jay Steven; Harris, Gordon J.; Sorensen, A; McKenna, Michael John; Barker, Frederick George (Springer Nature, 2009)Neurofibromatosis type 2 (NF2) is a tumor suppressor gene syndrome characterized by multiple schwannomas, especially vestibular schwannomas (VS), and meningiomas. Anticancer drug trials are now being explored, but there ... -
Sulforaphane, a natural component of broccoli, inhibits vestibular schwannoma growth in vitro and in vivo
Kim, Bo Gyung; Fujita, Takeshi; Stankovic, Konstantina M.; Welling, D. Bradley; Moon, In Seok; Choi, Jae Young; Yun, Jieun; Kang, Jong Soon; Lee, Jong Dae (Nature Publishing Group, 2016)Vestibular schwannoma (VS) is an intracranial tumor that causes significant morbidity, including hearing loss, tinnitus, dizziness, and possibly even death from brainstem compression. However, FDA-approved pharmacologic ...