Browsing by Author "Chung, Su Wol"
Now showing items 1-1 of 1
-
Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia
Lopez-Guzman, Silvia; Riascos, Dario F.; Macias, Alvaro A.; Layne, Matthew D.; Harris, Cailin; Reeves, Raymond; Baron, Rebecca Marlene; Cheng, Guiying; Chung, Su Wol; Von Andrian, Ulrich H.; Perrella, Mark A. (Public Library of Science, 2010)Background: The architectural transcription factor High Mobility Group-A1 (HMGA1) binds to the minor groove of AT-rich DNA and forms transcription factor complexes (“enhanceosomes”) that upregulate expression of select ...