Browsing by Author "Tullius, Stefan"

Now showing items 1-7 of 7

    • Current status of vascularized composite tissue allotransplantation 

      Edtinger, Karoline; Yang, Xiaoyong; Uehara, Hanae; Tullius, Stefan G. (BioMed Central, 2014)
      Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional ...

    • The importance of prevention of calciphylaxis in patients who are at risk and the potential fallibility of calcimimetics in the treatment of calciphylaxis for patients with secondary hyperparathyroidism 

      Khalpey, Zain; Nehs, Matthew A.; ElBardissi, Andrew W.; Semel, Marcus; Tullius, Stefan G. (Oxford University Press, 2009)
      A 43-year-old African American with end-stage renal disease (ESRD) associated with membranous nephropathy and a previously failed renal transplant had received cinacalcet to treat his secondary hyperparathyroidism. Serum ...

    • Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats 

      Werner, Wiebke; Sallmon, Hannes; Leder, Annekatrin; Lippert, Steffen; Reutzel-Selke, Anja; Morgül, Mehmet Haluk; Jonas, Sven; Dame, Christof; Neuhaus, Peter; Iacomini, John; Tullius, Stefan G; Sauer, Igor M; Raschzok, Nathanael (BioMed Central, 2014)
      Background: Studies on liver regeneration following partial hepatectomy (PH) have identified several microRNAs (miRNAs) that show a regulated expression pattern. These studies involve major surgery to access the liver, ...

    • NAD+ protects against EAE by regulating CD4+ T-cell differentiation 

      Tullius, Stefan G.; Biefer, Hector Rodriguez Cetina; Li, Suyan; Trachtenberg, Alexander J.; Edtinger, Karoline; Quante, Markus; Krenzien, Felix; Uehara, Hirofumi; Yang, Xiaoyong; Kissick, Haydn T.; Kuo, Winston P.; Ghiran, Ionita; de la Fuente, Miguel A.; Arredouani, Mohamed S.; Camacho, Virginia; Tigges, John C.; Toxavidis, Vasilis; El Fatimy, Rachid; Smith, Brian D.; Vasudevan, Anju; ElKhal, Abdallah (Nature Pub. Group, 2014)
      CD4+ T cells are involved in the development of autoimmunity, including multiple sclerosis (MS). Here we show that nicotinamide adenine dinucleotide (NAD+) blocks experimental autoimmune encephalomyelitis (EAE), a mouse ...

    • NAD+ regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4+ CD25+ Foxp3+ T cells independent 

      Elkhal, Abdallah; Rodriguez Cetina Biefer, Hector; Heinbokel, Timm; Uehara, Hirofumi; Quante, Markus; Seyda, Midas; Schuitenmaker, Jeroen M.; Krenzien, Felix; Camacho, Virginia; de la Fuente, Miguel A.; Ghiran, Ionita; Tullius, Stefan G. (Nature Publishing Group, 2016)
      CD4+ CD25+ Foxp3+ Tregs have been shown to play a central role in immune homeostasis while preventing from fatal inflammatory responses, while Th17 cells have traditionally been recognized as pro-inflammatory mediators ...

    • Prolonged Graft Survival in Older Recipient Mice Is Determined by Impaired Effector T-Cell but Intact Regulatory T-Cell Responses 

      Denecke, Christian; Bedi, Damanpreet Singh; Ge, Xupeng; Kim, Irene Kyung-eun; Jurisch, Anke; Weiland, Anne; Habicht, Antje; Li, Xian Chang; Tullius, Stefan Gunther (Public Library of Science, 2010)
      Elderly organ transplant recipients represent a fast growing segment of patients on the waiting list. We examined age-dependent CD4+ T-cell functions in a wild-type (WT) and a transgenic mouse transplant model and analyzed ...

    • Three Patients with Full Facial Transplantation 

      Pomahac, Bohdan; Pribaz, Julian Joseph; Eriksson, Elof; Bueno, Ericka; Diaz-Siso, J. Rodrigo; Rybicki, Frank John; Annino, Donald James; Orgill, Dennis Paul; Caterson, Edward J; Caterson, Stephanie A.; Carty, Matthew Jonathan; Chun, Yoon Sun; Sampson, Christian Edward; Janis, Jeffrey E.; Alam, Daniel S.; Saavedra, Arturo; Molnar, Joseph A.; Edrich, Thomas; Marty, Francisco Miguel; Tullius, Stefan Gunther (New England Journal of Medicine (NEJM/MMS), 2012)
      Unlike conventional reconstruction, facial transplantation seeks to correct severe deformities in a single operation. We report on three patients who received full-face transplants at our institution in 2011 in operations ...