Browsing by Author "Hansen, Anders Sejr"

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Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression

Hansen, Anders Sejr; O’Shea, Erin K (Wiley-Blackwell, 2013)

Numerous transcription factors (TFs) encode information about upstream signals in the dynamics of their activation, but how downstream genes decode these dynamics remains poorly understood. Using microfluidics to control ...
Promoter Decoding of Transcription Factor Translocation Dynamics

Hansen, Anders Sejr (2015-05-11)

Many cellular signaling pathways exhibit a bowtie topology: multiple distinct signal inputs converge on a single master transcription factor, which controls the expression of downstream genes. Recent evidence suggests that ...