Browsing by Author "Leviton, Alan"
Now showing items 1-7 of 7
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Are Preterm Newborns Who Have Relative Hyperthyrotropinemia at Increased Risk of Brain Damage?
Korzeniewski, Steven J.; Soto-Rivera, Carmen L.; Fichorova, Raina; Allred, Elizabeth N.; Kuban, Karl C. K.; O’Shea, T. Michael; Paneth, Nigel; Agus, Michael; Dammann, Olaf; Leviton, Alan (Walter de Gruyter GmbH, 2014-11)Background We sought to disentangle the contributions of hyperthyrotropinemia (an indicator of thyroid dysfunction) (HTT) and intermittent or sustained systemic inflammation (ISSI) to structural and functional indicators ... -
Early Blood Gas Predictors of Bronchopulmonary Dysplasia in Extremely Low Gestational Age Newborns
Sriram, Sudhir; Condie, Joy; Schreiber, Michael D.; Batton, Daniel G.; Shah, Bhavesh; Bose, Carl; Laughon, Matthew; Van Marter, Linda J.; Allred, Elizabeth N.; Leviton, Alan (Hindawi Publishing Corporation, 2014)Aim. To determine among infants born before the 28th week of gestation to what extent blood gas abnormalities during the first three postnatal days provide information about the risk of bronchopulmonary dysplasia (BPD). ... -
Early Nutrition and Weight Gain in Preterm Newborns and the Risk of Retinopathy of Prematurity
VanderVeen, Deborah K.; Martin, Camilia R.; Mehendale, Reshma; Allred, Elizabeth N.; Dammann, Olaf; Leviton, Alan (Public Library of Science, 2013)Objective: To identify nutritional and weight gain limitations associated with retinopathy of prematurity (ROP) severity among very preterm newborns. Patients and Methods 1180 infants <28 weeks GA at birth with ROP examination ... -
Elevated Endogenous Erythropoietin Concentrations Are Associated with Increased Risk of Brain Damage in Extremely Preterm Neonates
Korzeniewski, Steven J.; Allred, Elizabeth; Logan, J. Wells; Fichorova, Raina N.; Engelke, Stephen; Kuban, Karl C. K.; O’Shea, T. Michael; Paneth, Nigel; Holm, Mari; Dammann, Olaf; Leviton, Alan (Public Library of Science, 2015)Background: We sought to determine, in very preterm infants, whether elevated perinatal erythropoietin (EPO) concentrations are associated with increased risks of indicators of brain damage, and whether this risk differs ... -
Perturbation of Gene Expression of the Chromatin Remodeling Pathway in Premature Newborns at Risk for Bronchopulmonary Dysplasia
Cohen, Jennifer Naomi; Van Marter, Linda Joanne; Sun, Yao; Allred, Elizabeth Newton; Leviton, Alan; Kohane, Isaac Samuel (BioMed Central, 2007)Background: One-third to one-half of all infants born before the 28th week of gestation develop bronchopulmonary dysplasia (BPD). Inflammatory regulators appear to be involved in the pathogenesis of BPD, possibly beginning ... -
Systems approach to the study of brain damage in the very preterm newborn
Leviton, Alan; Gressens, Pierre; Wolkenhauer, Olaf; Dammann, Olaf (Frontiers Media S.A., 2015)Background:: A systems approach to the study of brain damage in very preterm newborns has been lacking. Methods:: In this perspective piece, we offer encephalopathy of prematurity as an example of the complexity and ... -
Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation
Leviton, Alan; Fichorova, Raina N.; O’Shea, T. Michael; Kuban, Karl; Paneth, Nigel; Dammann, Olaf; Allred, Elizabeth N. (2013)Background: We sought to disentangle the contributions of perinatal systemic inflammation and small for gestational age (SGA) to the occurrence of low Bayley Mental Development Indices (MDIs) at age 2 years. Method We ...