Browsing by Author "Perez-Atayde, Antonio"

Now showing items 1-6 of 6

    • A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study 

      Fountzilas, Elena; Kelly, Andrew D; Perez-Atayde, Antonio Rafael; Goldsmith, Jeffrey David; Konstantinopoulos, Panagiotis; Francoeur, Nancy; Correll, Mick; Rubio, Renee; Hu, Lan; Gebhardt, Mark Clyde; Quackenbush, John; Spentzos, Dimitrios (BioMed Central, 2012)
      Background: MicroRNAs (miRNAs) are nucleic acid regulators of many human mRNAs, and are associated with many tumorigenic processes. miRNA expression levels have been used in profiling studies, but some evidence suggests ...

    • MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32 

      Kelly, Andrew D; Haibe-Kains, Benjamin; Janeway, Katherine A; Hill, Katherine E; Howe, Eleanor; Goldsmith, Jeffrey; Kurek, Kyle; Perez-Atayde, Antonio R; Francoeur, Nancy; Fan, Jian-Bing; April, Craig; Schneider, Hal; Gebhardt, Mark C; Culhane, Aedin; Quackenbush, John; Spentzos, Dimitrios (BioMed Central, 2013)
      Background: Although microRNAs (miRNAs) are implicated in osteosarcoma biology and chemoresponse, miRNA prognostic models are still needed, particularly because prognosis is imperfectly correlated with chemoresponse. ...

    • Recurrent EML4–NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy 

      Church, Alanna; Calicchio, Monica; Nardi, Valentina; Skálová, Alena; Pinto, Andre; Dillon, Deborah; Gomez-Fernandez, Carmen; Manoj, Namitha; Haimes, Josh; Stahl, Joshua; Dela Cruz, Filemon; Tannenbaum-Dvir, Sarah; Glade-Bender, Julia; Kung, Andrew; DuBois, Steven; Kozakewich, Harry; Janeway, Katherine; Perez-Atayde, Antonio; Harris, Marian (Springer Science and Business Media LLC, 2017-11-03)

    • The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy 

      Ahmad, Ferhaan; Banerjee, Sanjay K.; Lage, Michele L.; Huang, Xueyin N.; Saba, Samir; Rager, Jennifer; Janczewski, Andrzej M.; Tobita, Kimimasa; Tinney, Joseph P.; Moskowitz, Ivan P.; Keller, Bradley B.; Mathier, Michael A.; Shroff, Sanjeev G.; Smith, Stephen H.; Conner, David Atwater; Perez-Atayde, Antonio Rafael; Seidman, Christine Edry; Seidman, Jonathan G. (Public Library of Science, 2008)
      Background: Hypertrophic (HCM) and dilated (DCM) cardiomyopathies result from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2). We determined whether TNNT2 mutations cause cardiomyopathies by altering ...

    • Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain 

      He, Shuning; Mansour, Marc R; Zimmerman, Mark W; Ki, Dong Hyuk; Layden, Hillary M; Akahane, Koshi; Gjini, Evisa; de Groh, Eric D; Perez-Atayde, Antonio R; Zhu, Shizhen; Epstein, Jonathan A; Look, A Thomas (eLife Sciences Publications, Ltd, 2016)
      Earlier reports showed that hyperplasia of sympathoadrenal cell precursors during embryogenesis in Nf1-deficient mice is independent of Nf1’s role in down-modulating RAS-MAPK signaling. We demonstrate in zebrafish that nf1 ...

    • YAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma 

      LaQuaglia, Michael J.; Grijalva, James L.; Mueller, Kaly A.; Perez-Atayde, Antonio R.; Kim, Heung Bae; Sadri-Vakili, Ghazaleh; Vakili, Khashayar (Nature Publishing Group, 2016)
      Pediatric hepatocellular carcinoma (HCC) is a rare tumor which is associated with an extremely high mortality rate due to lack of effective chemotherapy. Recently, the Hippo pathway and its transcriptional co-activator ...