Browsing by Author "Morris, Robert"
Now showing items 1-4 of 4
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dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes
Korenjak, Michael; Kwon, Eunjeong; Morris, Robert T.; Anderssen, Endre; Amzallag, Arnaud; Ramaswamy, Sridhar; Dyson, Nicholas J. (Oxford University Press, 2014)dREAM complexes represent the predominant form of E2F/RBF repressor complexes in Drosophila. dREAM associates with thousands of sites in the fly genome but its mechanism of action is unknown. To understand the genomic ... -
Easy Freshness with Pequod Cache Joins
Kate, Bryan Nathan (2015-01-14)This thesis presents the design of Pequod, a distributed, application-level Web cache. Web developers store data in application-level caches to avoid expensive operations on persistent storage. While useful for reducing ... -
Neural processes underlying self- and other-related lies: An individual difference approach using fMRI
Ganis, Giorgio; Morris, Robert; Kosslyn, Stephen Michael (Informa UK Limited, 2009)Two hypotheses were tested using a novel individual differences approach, which identifies rate-limiting brain regions, that is, brain regions in which variations in neural activity predict variations in behavioral performance. ... -
SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
Tajima, Ken; Yae, Toshifumi; Javaid, Sarah; Tam, Oliver; Comaills, Valentine; Morris, Robert; Wittner, Ben S.; Liu, Mingzhu; Engstrom, Amanda; Takahashi, Fumiyuki; Black, Joshua C.; Ramaswamy, Sridhar; Shioda, Toshihiro; Hammell, Molly; Haber, Daniel A.; Whetstine, Johnathan R.; Maheswaran, Shyamala (Nature Pub. Group, 2015)Expression of the p53-inducible antiproliferative gene BTG2 is suppressed in many cancers in the absence of inactivating gene mutations, suggesting alternative mechanisms of silencing. Using a shRNA screen targeting 43 ...