Now showing items 1-2 of 2

    • TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation 

      Greenfeld, Hannah; Takasaki, Kaoru; Walsh, Michael J.; Ersing, Ina; Bernhardt, Katharina; Ma, Yijie; Fu, Bishi; Ashbaugh, Camille W.; Cabo, Jackson; Mollo, Sarah B.; Zhou, Hufeng; Li, Shitao; Gewurz, Benjamin E. (Public Library of Science, 2015)
      The Epstein-Barr virus (EBV) encoded oncoprotein Latent Membrane Protein 1 (LMP1) signals through two C-terminal tail domains to drive cell growth, survival and transformation. The LMP1 membrane-proximal TES1/CTAR1 domain ...
    • TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase 

      Fu, Bishi; Wang, Lingyan; Ding, Hao; Schwamborn, Jens C.; Li, Shitao; Dorf, Martin E. (Public Library of Science, 2015)
      Polymerase basic protein 1 (PB1) is the catalytic core of the influenza A virus (IAV) RNA polymerase complex essential for viral transcription and replication. Understanding the intrinsic mechanisms which block PB1 function ...